Tags

Type your tag names separated by a space and hit enter

Triterpenoidal saponins of Pulsatilla koreana roots.
Phytochemistry. 2010 Nov; 71(16):1892-9.P

Abstract

Sixteen (1-16) triterpenoidal saponins were isolated from the roots of Pulsatilla koreana, of which four were determined as the previously unknown 23-hydroxy-3β-[(O-α-L-arabinopyranosyl)oxy]lup-20(29)-en-28-oic acid 28-O-β-D-glucopyranosyl ester (1), 23-hydroxy-3β-[(O-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl)oxy]lup-20(29)-en-28-oic acid 28-O-β-D-glucopyranosyl ester (2), 3β-[(O-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl)oxy]lup-20(29)-en-28-oic acid 28-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl ester (3), and 3β-[(O-α-L-rhamnopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→4)]-α-L-arabinopyranosyl)oxy]lup-20(29)-en-28-oic acid 28-O-α-L-rhamnopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl ester (4), respectively, based on spectroscopic analysis. The inhibition of the lipopolysaccharide-induced nitric oxide production of sixteen isolated compounds was evaluated in RAW 264.7 cells at concentrations ranging from 1 μM to 100 μM.

Authors+Show Affiliations

College of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University, Daehak-Dong, Gwanak-Gu, Seoul 151-742, Republic of Korea.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20800858

Citation

Yang, Heejung, et al. "Triterpenoidal Saponins of Pulsatilla Koreana Roots." Phytochemistry, vol. 71, no. 16, 2010, pp. 1892-9.
Yang H, Cho YW, Kim SH, et al. Triterpenoidal saponins of Pulsatilla koreana roots. Phytochemistry. 2010;71(16):1892-9.
Yang, H., Cho, Y. W., Kim, S. H., Kim, Y. C., & Sung, S. H. (2010). Triterpenoidal saponins of Pulsatilla koreana roots. Phytochemistry, 71(16), 1892-9. https://doi.org/10.1016/j.phytochem.2010.07.013
Yang H, et al. Triterpenoidal Saponins of Pulsatilla Koreana Roots. Phytochemistry. 2010;71(16):1892-9. PubMed PMID: 20800858.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Triterpenoidal saponins of Pulsatilla koreana roots. AU - Yang,Heejung, AU - Cho,Young Woong, AU - Kim,Seung Hyun, AU - Kim,Young Choong, AU - Sung,Sang Hyun, Y1 - 2010/08/26/ PY - 2009/10/30/received PY - 2010/07/21/revised PY - 2010/07/26/accepted PY - 2010/8/31/entrez PY - 2010/8/31/pubmed PY - 2011/1/19/medline SP - 1892 EP - 9 JF - Phytochemistry JO - Phytochemistry VL - 71 IS - 16 N2 - Sixteen (1-16) triterpenoidal saponins were isolated from the roots of Pulsatilla koreana, of which four were determined as the previously unknown 23-hydroxy-3β-[(O-α-L-arabinopyranosyl)oxy]lup-20(29)-en-28-oic acid 28-O-β-D-glucopyranosyl ester (1), 23-hydroxy-3β-[(O-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl)oxy]lup-20(29)-en-28-oic acid 28-O-β-D-glucopyranosyl ester (2), 3β-[(O-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl)oxy]lup-20(29)-en-28-oic acid 28-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl ester (3), and 3β-[(O-α-L-rhamnopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→4)]-α-L-arabinopyranosyl)oxy]lup-20(29)-en-28-oic acid 28-O-α-L-rhamnopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl ester (4), respectively, based on spectroscopic analysis. The inhibition of the lipopolysaccharide-induced nitric oxide production of sixteen isolated compounds was evaluated in RAW 264.7 cells at concentrations ranging from 1 μM to 100 μM. SN - 1873-3700 UR - https://www.unboundmedicine.com/medline/citation/20800858/Triterpenoidal_saponins_of_Pulsatilla_koreana_roots_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0031-9422(10)00298-0 DB - PRIME DP - Unbound Medicine ER -