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Combined use of crystalloid preload and low dose spinal anesthesia for preventing hypotension in spinal anesthesia for cesarean delivery: a randomized controlled trial.
Middle East J Anaesthesiol 2010; 20(5):667-72ME

Abstract

BACKGROUND AND OBJECTIVE

Spinal anaesthesia for caesarean section is commonly associated with hypotension and crystalloid preload is widely recommended. Low-dose spinal appears to cause less hypotension. The aim of this study was to investigate whether the combined use of crystalloid preload and low dose spinal anaesthesia might further reduce the rates of hypotension.

METHODS

Sixty-two patients were randomly assigned to two groups: crystalloid preload anaesthesia (P): received a rapid infusion of 20 mL/kg lactated Ringer's solution (LR), and no preload anaesthesia (N). The incidence of hypotension and the amount of ephedrine used to treat it were compared. Spinal anaesthesia was performed with 0.5% isobaric bupivacaine 7.5 mg and fentanyl 10 microg and morphine 100 microg.

RESULTS

The incidence of hypotension was similar in the P and N groups. Same doses of ephedrine were required to treat hypotension in the two groups.

CONCLUSION

Crystalloid preload combined with low-dose spinal anaesthesia do not reduce the incidence of hypotension nor its severity.

Authors+Show Affiliations

Department of Thoracic Surgery, Abderrahmen Mami Hospital, Ariana, Tunisia.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

20803854

Citation

Ouerghi, Sonia, et al. "Combined Use of Crystalloid Preload and Low Dose Spinal Anesthesia for Preventing Hypotension in Spinal Anesthesia for Cesarean Delivery: a Randomized Controlled Trial." Middle East Journal of Anaesthesiology, vol. 20, no. 5, 2010, pp. 667-72.
Ouerghi S, Bougacha MA, Frikha N, et al. Combined use of crystalloid preload and low dose spinal anesthesia for preventing hypotension in spinal anesthesia for cesarean delivery: a randomized controlled trial. Middle East J Anaesthesiol. 2010;20(5):667-72.
Ouerghi, S., Bougacha, M. A., Frikha, N., Mestiri, T., Ben Ammar, M. S., & Mebazaa, M. S. (2010). Combined use of crystalloid preload and low dose spinal anesthesia for preventing hypotension in spinal anesthesia for cesarean delivery: a randomized controlled trial. Middle East Journal of Anaesthesiology, 20(5), pp. 667-72.
Ouerghi S, et al. Combined Use of Crystalloid Preload and Low Dose Spinal Anesthesia for Preventing Hypotension in Spinal Anesthesia for Cesarean Delivery: a Randomized Controlled Trial. Middle East J Anaesthesiol. 2010;20(5):667-72. PubMed PMID: 20803854.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Combined use of crystalloid preload and low dose spinal anesthesia for preventing hypotension in spinal anesthesia for cesarean delivery: a randomized controlled trial. AU - Ouerghi,Sonia, AU - Bougacha,Mohamed A, AU - Frikha,Nabil, AU - Mestiri,Taher, AU - Ben Ammar,Mohamed S, AU - Mebazaa,Mhamed S, PY - 2010/9/1/entrez PY - 2010/9/2/pubmed PY - 2010/9/16/medline SP - 667 EP - 72 JF - Middle East journal of anaesthesiology JO - Middle East J Anaesthesiol VL - 20 IS - 5 N2 - BACKGROUND AND OBJECTIVE: Spinal anaesthesia for caesarean section is commonly associated with hypotension and crystalloid preload is widely recommended. Low-dose spinal appears to cause less hypotension. The aim of this study was to investigate whether the combined use of crystalloid preload and low dose spinal anaesthesia might further reduce the rates of hypotension. METHODS: Sixty-two patients were randomly assigned to two groups: crystalloid preload anaesthesia (P): received a rapid infusion of 20 mL/kg lactated Ringer's solution (LR), and no preload anaesthesia (N). The incidence of hypotension and the amount of ephedrine used to treat it were compared. Spinal anaesthesia was performed with 0.5% isobaric bupivacaine 7.5 mg and fentanyl 10 microg and morphine 100 microg. RESULTS: The incidence of hypotension was similar in the P and N groups. Same doses of ephedrine were required to treat hypotension in the two groups. CONCLUSION: Crystalloid preload combined with low-dose spinal anaesthesia do not reduce the incidence of hypotension nor its severity. SN - 0544-0440 UR - https://www.unboundmedicine.com/medline/citation/20803854/Combined_use_of_crystalloid_preload_and_low_dose_spinal_anesthesia_for_preventing_hypotension_in_spinal_anesthesia_for_cesarean_delivery:_a_randomized_controlled_trial_ L2 - https://medlineplus.gov/cesareansection.html DB - PRIME DP - Unbound Medicine ER -