TY - JOUR T1 - [Xanthones of Comastoma pedunlulatum]. AU - Yuan,Yi, AU - Cui,Baosong, AU - Zhang,Ying, AU - Li,Shuai, PY - 2010/9/7/entrez PY - 2010/9/8/pubmed PY - 2010/10/6/medline SP - 1577 EP - 9 JF - Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica JO - Zhongguo Zhong Yao Za Zhi VL - 35 IS - 12 N2 - The xanthones in the ethyl acetate extract of Comastoma pedunlulatum were investigated. The chromatographic and spectroscopic techniques were used to isolate and identify the constituents. Nine xanthones were isolated from the active parts of the ethyl acetate portion of the 70% ethanolic extract of C. Pedunlulatum, which possess the protective activity against hepatocyte damage caused by DL-GalN, and identified as 1,8-dihydroxy-2,6-dimethoxyxanthone (1), 8-hydroxy-1,2,6-trimethoxyxanthone (2), 1,6,8-trihydroxy-2-methoxyxanthone (3), 1,8-dihydroxy-3,5-dimethoxyxanthone (4), 1-hydroxy-3,5,8-trimethoxyxanthone (5), 1 -hydroxy-3,7-dimethoxyxanthone (6), 1,2,6,8-tetrahydroxyxanthone (7), 1,3,7-trihydroxy4- methoxyxanthone (8), 6,8-dihydroxy-1, 2-dimethoxyxanthone (9). Among them, compounds 6-9 were isolated from the genus Comastoma for the fist time. SN - 1001-5302 UR - https://www.unboundmedicine.com/medline/citation/20815211/[Xanthones_of_Comastoma_pedunlulatum]_ DB - PRIME DP - Unbound Medicine ER -