Tags

Type your tag names separated by a space and hit enter

Distal oesophageal ph monitoring for gastro-oesophageal reflux.
Ir Med J. 1990 Dec; 83(4):142-4.IM

Abstract

We investigated eight hour distal intra-oesophageal ph testing to see if this could replace the traditional 24 hour test period without significant loss of sensitivity in the diagnosis of gastro-oesophageal reflux (GOR) disease in symptomatic refluxers. Thirty-four patients were tested, all of whom had classical De Meester symptoms of GOR. All patients were admitted to hospital and commenced on 24 hour ambulant ph monitoring of the distal oesophagus. This was followed by a period of eight hour testing. The following variables were determined: (i) total reflux time, (ii) number of reflux episodes (total, upright and supine), (iii) longest episode of reflux, (iv) percent of time that ph was below four (total, upright and supine). All patients underwent endoscopic examination of the oesophagus subsequently. Twenty four hour monitoring resulted in a positive diagnosis of GOR in 26 of 34 patients, giving an overall sensitivity of 75%. Eight hour testing was positive in 23 patients (sensitivity of 68%, not significantly different). The best correlations were obtained when comparing total reflux episodes (r = 0.75, p less than 0.001), and the percent time ph less than 4 (total) (r = 0.69, p less than 0.001). Nineteen patients had evidence of oesophagitis on endoscopy, and in all such patients both eight and 24 hour testing were positive. We conclude therefore, that eight hour ph monitoring can be reliably used in the diagnosis of pathological GOR in patients symptomatic for acid reflux.

Authors+Show Affiliations

Department of Surgery, University College Hospital, Galway.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

2081668

Citation

Horgan, P, et al. "Distal Oesophageal Ph Monitoring for Gastro-oesophageal Reflux." Irish Medical Journal, vol. 83, no. 4, 1990, pp. 142-4.
Horgan P, Waldron D, Saleh H, et al. Distal oesophageal ph monitoring for gastro-oesophageal reflux. Ir Med J. 1990;83(4):142-4.
Horgan, P., Waldron, D., Saleh, H., Byrne, J., Mooney, E., McGuire, M., & Given, H. F. (1990). Distal oesophageal ph monitoring for gastro-oesophageal reflux. Irish Medical Journal, 83(4), 142-4.
Horgan P, et al. Distal Oesophageal Ph Monitoring for Gastro-oesophageal Reflux. Ir Med J. 1990;83(4):142-4. PubMed PMID: 2081668.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Distal oesophageal ph monitoring for gastro-oesophageal reflux. AU - Horgan,P, AU - Waldron,D, AU - Saleh,H, AU - Byrne,J, AU - Mooney,E, AU - McGuire,M, AU - Given,H F, PY - 1990/12/1/pubmed PY - 1990/12/1/medline PY - 1990/12/1/entrez SP - 142 EP - 4 JF - Irish medical journal JO - Ir Med J VL - 83 IS - 4 N2 - We investigated eight hour distal intra-oesophageal ph testing to see if this could replace the traditional 24 hour test period without significant loss of sensitivity in the diagnosis of gastro-oesophageal reflux (GOR) disease in symptomatic refluxers. Thirty-four patients were tested, all of whom had classical De Meester symptoms of GOR. All patients were admitted to hospital and commenced on 24 hour ambulant ph monitoring of the distal oesophagus. This was followed by a period of eight hour testing. The following variables were determined: (i) total reflux time, (ii) number of reflux episodes (total, upright and supine), (iii) longest episode of reflux, (iv) percent of time that ph was below four (total, upright and supine). All patients underwent endoscopic examination of the oesophagus subsequently. Twenty four hour monitoring resulted in a positive diagnosis of GOR in 26 of 34 patients, giving an overall sensitivity of 75%. Eight hour testing was positive in 23 patients (sensitivity of 68%, not significantly different). The best correlations were obtained when comparing total reflux episodes (r = 0.75, p less than 0.001), and the percent time ph less than 4 (total) (r = 0.69, p less than 0.001). Nineteen patients had evidence of oesophagitis on endoscopy, and in all such patients both eight and 24 hour testing were positive. We conclude therefore, that eight hour ph monitoring can be reliably used in the diagnosis of pathological GOR in patients symptomatic for acid reflux. SN - 0332-3102 UR - https://www.unboundmedicine.com/medline/citation/2081668/Distal_oesophageal_ph_monitoring_for_gastro_oesophageal_reflux_ L2 - https://medlineplus.gov/gerd.html DB - PRIME DP - Unbound Medicine ER -