Tags

Type your tag names separated by a space and hit enter

Pandemic influenza A(H1N1) 2009 and respiratory syncytial virus associated hospitalizations.
J Infect. 2010 Nov; 61(5):382-90.JI

Abstract

OBJECTIVES

To determine the contribution of influenza and respiratory syncytial virus (RSV) as the cause of lower respiratory tract infection (LRTI) associated hospitalizations during the first year of the influenza A(H1N1) 2009 pandemic and to assess the severity of illness during the second pandemic wave.

METHODS

Patients admitted with LRTI from April 2009 through March 2010 were assessed for the presence of influenza and RSV. Pandemic influenza virus was detected by means of a nested RT-PCR assay and/or the CDC's real time-PCR protocol. RSV was detected using a one-step RT-PCR assay. The characteristics of patients admitted during the first and second pandemic outbreaks were compared.

RESULTS

657 patients with LRTI were admitted during the study period. Pandemic influenza virus was detected in 180 and RSV in 133. Influenza was the most common cause of infection in adults, while RSV was more common in children. There were no differences in disease severity between the first and second pandemic outbreaks.

CONCLUSIONS

Pandemic influenza virus was associated to increased numbers of hospitalizations and deaths; particularly in adults. The severity of the first and second pandemic outbreaks was similar. RSV continues to be the main pathogen responsible for hospitalizations in young children.

Authors+Show Affiliations

Microbiology Department, Facultad de Medicina, Universidad Autónoma de San Luis Potosí, Avenida Venustiano Carranza 2405, San Luis Potosí, S.L.P. 78210, Mexico.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20816695

Citation

Lovato-Salas, Fernando, et al. "Pandemic Influenza A(H1N1) 2009 and Respiratory Syncytial Virus Associated Hospitalizations." The Journal of Infection, vol. 61, no. 5, 2010, pp. 382-90.
Lovato-Salas F, Matienzo-Serment L, Monjarás-Ávila C, et al. Pandemic influenza A(H1N1) 2009 and respiratory syncytial virus associated hospitalizations. J Infect. 2010;61(5):382-90.
Lovato-Salas, F., Matienzo-Serment, L., Monjarás-Ávila, C., Godoy-Lozano, E. E., Comas-García, A., Aguilera-Barragán, M., Durham-González, A., Contreras-Vidales, S., Ochoa-Pérez, U., Gómez-Gómez, A., García-Sepúlveda, C. A., & Noyola, D. E. (2010). Pandemic influenza A(H1N1) 2009 and respiratory syncytial virus associated hospitalizations. The Journal of Infection, 61(5), 382-90. https://doi.org/10.1016/j.jinf.2010.08.008
Lovato-Salas F, et al. Pandemic Influenza A(H1N1) 2009 and Respiratory Syncytial Virus Associated Hospitalizations. J Infect. 2010;61(5):382-90. PubMed PMID: 20816695.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pandemic influenza A(H1N1) 2009 and respiratory syncytial virus associated hospitalizations. AU - Lovato-Salas,Fernando, AU - Matienzo-Serment,Lorena, AU - Monjarás-Ávila,César, AU - Godoy-Lozano,Elizabeth E, AU - Comas-García,Andreu, AU - Aguilera-Barragán,Marcela, AU - Durham-González,Adriana, AU - Contreras-Vidales,Soledad, AU - Ochoa-Pérez,Uciel, AU - Gómez-Gómez,Alejandro, AU - García-Sepúlveda,Christian A, AU - Noyola,Daniel E, Y1 - 2010/09/20/ PY - 2010/06/22/received PY - 2010/08/24/revised PY - 2010/08/24/accepted PY - 2010/9/7/entrez PY - 2010/9/8/pubmed PY - 2011/9/3/medline SP - 382 EP - 90 JF - The Journal of infection JO - J Infect VL - 61 IS - 5 N2 - OBJECTIVES: To determine the contribution of influenza and respiratory syncytial virus (RSV) as the cause of lower respiratory tract infection (LRTI) associated hospitalizations during the first year of the influenza A(H1N1) 2009 pandemic and to assess the severity of illness during the second pandemic wave. METHODS: Patients admitted with LRTI from April 2009 through March 2010 were assessed for the presence of influenza and RSV. Pandemic influenza virus was detected by means of a nested RT-PCR assay and/or the CDC's real time-PCR protocol. RSV was detected using a one-step RT-PCR assay. The characteristics of patients admitted during the first and second pandemic outbreaks were compared. RESULTS: 657 patients with LRTI were admitted during the study period. Pandemic influenza virus was detected in 180 and RSV in 133. Influenza was the most common cause of infection in adults, while RSV was more common in children. There were no differences in disease severity between the first and second pandemic outbreaks. CONCLUSIONS: Pandemic influenza virus was associated to increased numbers of hospitalizations and deaths; particularly in adults. The severity of the first and second pandemic outbreaks was similar. RSV continues to be the main pathogen responsible for hospitalizations in young children. SN - 1532-2742 UR - https://www.unboundmedicine.com/medline/citation/20816695/Pandemic_influenza_A_H1N1__2009_and_respiratory_syncytial_virus_associated_hospitalizations_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0163-4453(10)00256-2 DB - PRIME DP - Unbound Medicine ER -