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[Evaluation of the value of ultrasound-guided core needle biopsy in the diagnosis of breast lesions].
Zhonghua Zhong Liu Za Zhi. 2010 Jun; 32(6):470-1.ZZ

Abstract

OBJECTIVE

To investigate the accuracy, consistency and related affecting factors in pathological results of breast lesions diagnosed by ultrasound-guided core needle biopsy (CNB) and conventional excision histopathology.

METHODS

The clinical data of 177 consecutive cases of breast lesions examined by ultrasound-guided CNB and subsequently excised were reviewed from Jan. 2003 to Nov. 2009. The agreement of pathological diagnosis between the CNB and subsequent excision pathology was analyzed.

RESULTS

There were 136 cancers in the final diagnosis after surgical excision among 386 breast lesions and 129 of them were diagnosed by CNB. The sensitivity (true positive) of CNB was 94.9%, false negative rate was 5.1%, specificity (true negative) was 100%, false positive rate 0, Youden's index was 0.949, and positive predictive value and negative predictive value were 100% and 85.4%, respectively. Condensation rate was 96.0% and Kappa value was 0.895.

CONCLUSION

Ultrasound-guided CNB with histopathological assessment is accurate in diagnosis of breast lesions and has a great consistency with conventional excision pathology. It is a reliable method for the diagnosis of breast lesions to avoid an over-reliance on excision pathological examination.

Authors+Show Affiliations

Breast Center, Shunyi Health Care Hospital for Women and Children, Beijing 101300, China. liyiborui@126.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Evaluation Study
Journal Article

Language

chi

PubMed ID

20819494

Citation

Li, Yi, et al. "[Evaluation of the Value of Ultrasound-guided Core Needle Biopsy in the Diagnosis of Breast Lesions]." Zhonghua Zhong Liu Za Zhi [Chinese Journal of Oncology], vol. 32, no. 6, 2010, pp. 470-1.
Li Y, Tong XS, Mu WM, et al. [Evaluation of the value of ultrasound-guided core needle biopsy in the diagnosis of breast lesions]. Zhonghua Zhong Liu Za Zhi. 2010;32(6):470-1.
Li, Y., Tong, X. S., Mu, W. M., Peng, W. G., Su, Y. J., Zhao, Y., & Sun, C. (2010). [Evaluation of the value of ultrasound-guided core needle biopsy in the diagnosis of breast lesions]. Zhonghua Zhong Liu Za Zhi [Chinese Journal of Oncology], 32(6), 470-1.
Li Y, et al. [Evaluation of the Value of Ultrasound-guided Core Needle Biopsy in the Diagnosis of Breast Lesions]. Zhonghua Zhong Liu Za Zhi. 2010;32(6):470-1. PubMed PMID: 20819494.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Evaluation of the value of ultrasound-guided core needle biopsy in the diagnosis of breast lesions]. AU - Li,Yi, AU - Tong,Xue-Song, AU - Mu,Wei-Min, AU - Peng,Wei-Guo, AU - Su,Ya-Jie, AU - Zhao,Yue, AU - Sun,Chao, PY - 2010/9/8/entrez PY - 2010/9/8/pubmed PY - 2011/5/27/medline SP - 470 EP - 1 JF - Zhonghua zhong liu za zhi [Chinese journal of oncology] JO - Zhonghua Zhong Liu Za Zhi VL - 32 IS - 6 N2 - OBJECTIVE: To investigate the accuracy, consistency and related affecting factors in pathological results of breast lesions diagnosed by ultrasound-guided core needle biopsy (CNB) and conventional excision histopathology. METHODS: The clinical data of 177 consecutive cases of breast lesions examined by ultrasound-guided CNB and subsequently excised were reviewed from Jan. 2003 to Nov. 2009. The agreement of pathological diagnosis between the CNB and subsequent excision pathology was analyzed. RESULTS: There were 136 cancers in the final diagnosis after surgical excision among 386 breast lesions and 129 of them were diagnosed by CNB. The sensitivity (true positive) of CNB was 94.9%, false negative rate was 5.1%, specificity (true negative) was 100%, false positive rate 0, Youden's index was 0.949, and positive predictive value and negative predictive value were 100% and 85.4%, respectively. Condensation rate was 96.0% and Kappa value was 0.895. CONCLUSION: Ultrasound-guided CNB with histopathological assessment is accurate in diagnosis of breast lesions and has a great consistency with conventional excision pathology. It is a reliable method for the diagnosis of breast lesions to avoid an over-reliance on excision pathological examination. SN - 0253-3766 UR - https://www.unboundmedicine.com/medline/citation/20819494/[Evaluation_of_the_value_of_ultrasound_guided_core_needle_biopsy_in_the_diagnosis_of_breast_lesions]_ L2 - http://journal.yiigle.com/LinkIn.do?linkin_type=pubmed&issn=0253-3766&year=2010&vol=32&issue=6&fpage=470 DB - PRIME DP - Unbound Medicine ER -