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[Potentiating effect of spirometric maneuver on bronchial responsiveness to methacholine in asthmatic subjects--the role of deep inspiration and forced expiration].
Rinsho Byori. 1990 Dec; 38(12):1378-82.RB

Abstract

We previously reported that spirometric maneuver (SM) had potentiating effect on bronchial responsiveness (BR) in asthmatic subjects but not in normal subjects. SM consists of deep inspiration to TLC (DI) and forced expiration to RV (FE). In this study, we examined the effect of SM, DI and FE on BR in 9 asthmatic subjects. Provocative concentration of methacholine producing a 35% fall in respiratory conductance (PC35-Grs) was significantly (p less than 0.02 and p less than 0.025) decreased from 0.34 mg/ml (GSEM, 1.51) to 0.16 mg/ml (GSEM, 1.45) and 0.14 mg/ml (GSEM, 1.51) by SM and DI, respectively but it was not altered by FE. These findings indicate that potentiating effect of SM on BR which is characteristic of asthma may be due to DI effect.

Authors+Show Affiliations

Central Clinical Laboratory, Kanazawa University Hospital.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

jpn

PubMed ID

2082038

Citation

Kamio, Y, et al. "[Potentiating Effect of Spirometric Maneuver On Bronchial Responsiveness to Methacholine in Asthmatic Subjects--the Role of Deep Inspiration and Forced Expiration]." Rinsho Byori. the Japanese Journal of Clinical Pathology, vol. 38, no. 12, 1990, pp. 1378-82.
Kamio Y, Fujimura M, Futamata H, et al. [Potentiating effect of spirometric maneuver on bronchial responsiveness to methacholine in asthmatic subjects--the role of deep inspiration and forced expiration]. Rinsho Byori. 1990;38(12):1378-82.
Kamio, Y., Fujimura, M., Futamata, H., Matsubara, F., & Matsuda, T. (1990). [Potentiating effect of spirometric maneuver on bronchial responsiveness to methacholine in asthmatic subjects--the role of deep inspiration and forced expiration]. Rinsho Byori. the Japanese Journal of Clinical Pathology, 38(12), 1378-82.
Kamio Y, et al. [Potentiating Effect of Spirometric Maneuver On Bronchial Responsiveness to Methacholine in Asthmatic Subjects--the Role of Deep Inspiration and Forced Expiration]. Rinsho Byori. 1990;38(12):1378-82. PubMed PMID: 2082038.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Potentiating effect of spirometric maneuver on bronchial responsiveness to methacholine in asthmatic subjects--the role of deep inspiration and forced expiration]. AU - Kamio,Y, AU - Fujimura,M, AU - Futamata,H, AU - Matsubara,F, AU - Matsuda,T, PY - 1990/12/1/pubmed PY - 1990/12/1/medline PY - 1990/12/1/entrez SP - 1378 EP - 82 JF - Rinsho byori. The Japanese journal of clinical pathology JO - Rinsho Byori VL - 38 IS - 12 N2 - We previously reported that spirometric maneuver (SM) had potentiating effect on bronchial responsiveness (BR) in asthmatic subjects but not in normal subjects. SM consists of deep inspiration to TLC (DI) and forced expiration to RV (FE). In this study, we examined the effect of SM, DI and FE on BR in 9 asthmatic subjects. Provocative concentration of methacholine producing a 35% fall in respiratory conductance (PC35-Grs) was significantly (p less than 0.02 and p less than 0.025) decreased from 0.34 mg/ml (GSEM, 1.51) to 0.16 mg/ml (GSEM, 1.45) and 0.14 mg/ml (GSEM, 1.51) by SM and DI, respectively but it was not altered by FE. These findings indicate that potentiating effect of SM on BR which is characteristic of asthma may be due to DI effect. SN - 0047-1860 UR - https://www.unboundmedicine.com/medline/citation/2082038/[Potentiating_effect_of_spirometric_maneuver_on_bronchial_responsiveness_to_methacholine_in_asthmatic_subjects__the_role_of_deep_inspiration_and_forced_expiration]_ L2 - https://medlineplus.gov/asthma.html DB - PRIME DP - Unbound Medicine ER -