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A reappraisal of the epidemiology of multiple sclerosis in Olmsted County, Minnesota.
Neurology 1990; 40(5):780-6Neur

Abstract

A review of multiple sclerosis (MS) case reports, using the unified record system at the Mayo Clinic for the Olmsted County population, revealed age- and sex-adjusted prevalence rates per 100,000 persons of 160 for Olmsted County and 173 for Rochester, Minnesota, on January 1, 1985. The annual age- and sex-adjusted incidence rate per 100,000 person-years from 1975 to 1984 for Olmsted County was 6.2 and for Rochester, 6.3. This incidence rate is significantly higher than what had been reported previously in Rochester (3.6/100,000) or in other communities. The estimated 25-year survival of the MS population was 76.2% +/- 4.5% compared with 87.7% for the general US white population of a similar age and sex. Survival for men was less than for women. There was no increase in survival for patients diagnosed with MS in more recent decades. No significant increase was found in cancer or autoimmune disease rates in the MS patients.

Authors+Show Affiliations

Department of Neurology, Mayo Clinic, Rochester, MN 55905.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

2082944

Citation

Wynn, D R., et al. "A Reappraisal of the Epidemiology of Multiple Sclerosis in Olmsted County, Minnesota." Neurology, vol. 40, no. 5, 1990, pp. 780-6.
Wynn DR, Rodriguez M, O'Fallon WM, et al. A reappraisal of the epidemiology of multiple sclerosis in Olmsted County, Minnesota. Neurology. 1990;40(5):780-6.
Wynn, D. R., Rodriguez, M., O'Fallon, W. M., & Kurland, L. T. (1990). A reappraisal of the epidemiology of multiple sclerosis in Olmsted County, Minnesota. Neurology, 40(5), pp. 780-6.
Wynn DR, et al. A Reappraisal of the Epidemiology of Multiple Sclerosis in Olmsted County, Minnesota. Neurology. 1990;40(5):780-6. PubMed PMID: 2082944.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A reappraisal of the epidemiology of multiple sclerosis in Olmsted County, Minnesota. AU - Wynn,D R, AU - Rodriguez,M, AU - O'Fallon,W M, AU - Kurland,L T, PY - 1990/5/1/pubmed PY - 1990/5/1/medline PY - 1990/5/1/entrez SP - 780 EP - 6 JF - Neurology JO - Neurology VL - 40 IS - 5 N2 - A review of multiple sclerosis (MS) case reports, using the unified record system at the Mayo Clinic for the Olmsted County population, revealed age- and sex-adjusted prevalence rates per 100,000 persons of 160 for Olmsted County and 173 for Rochester, Minnesota, on January 1, 1985. The annual age- and sex-adjusted incidence rate per 100,000 person-years from 1975 to 1984 for Olmsted County was 6.2 and for Rochester, 6.3. This incidence rate is significantly higher than what had been reported previously in Rochester (3.6/100,000) or in other communities. The estimated 25-year survival of the MS population was 76.2% +/- 4.5% compared with 87.7% for the general US white population of a similar age and sex. Survival for men was less than for women. There was no increase in survival for patients diagnosed with MS in more recent decades. No significant increase was found in cancer or autoimmune disease rates in the MS patients. SN - 0028-3878 UR - https://www.unboundmedicine.com/medline/citation/2082944/A_reappraisal_of_the_epidemiology_of_multiple_sclerosis_in_Olmsted_County_Minnesota_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=2082944.ui DB - PRIME DP - Unbound Medicine ER -