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Cow's milk protein allergy.
J Matern Fetal Neonatal Med. 2010 Oct; 23 Suppl 3:76-9.JM

Abstract

Cow's milk protein allergy (CMPA) affects 2-7.5% of children; persistence in adulthood is uncommon since a tolerance develops in 51% of cases within 2 years and 80% within 3-4 years. CMPA is an immunological reaction to one or more milk proteins: α-lactalbumin, β-lactoglobulin, casein, IgE or non-IgE associated, responsible of immediate or late onset symptoms. The suspicion of CMPA is based on detailed family and medical history, skin test, patch test, laboratory test, an elimination diet and food challenge. The general treatment for CMPA is dietary: elimination of cow's milk protein and introduction of extensively hydrolyzed whey or casein formula, amino acid formula, and soy formula. Extensively hydrolyzed whey or casein formula is recommended as first choice for infants in mild or moderate reactions, amino acid formula in severe CMPA and in cases with poor response to extensively hydrolysed whey or casein formula.

Authors+Show Affiliations

Children and Mother Care Department, Paediatrics Unit, S. Barbara Hospital, Iglesias.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

20836734

Citation

Solinas, C, et al. "Cow's Milk Protein Allergy." The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, vol. 23 Suppl 3, 2010, pp. 76-9.
Solinas C, Corpino M, Maccioni R, et al. Cow's milk protein allergy. J Matern Fetal Neonatal Med. 2010;23 Suppl 3:76-9.
Solinas, C., Corpino, M., Maccioni, R., & Pelosi, U. (2010). Cow's milk protein allergy. The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 23 Suppl 3, 76-9. https://doi.org/10.3109/14767058.2010.512103
Solinas C, et al. Cow's Milk Protein Allergy. J Matern Fetal Neonatal Med. 2010;23 Suppl 3:76-9. PubMed PMID: 20836734.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cow's milk protein allergy. AU - Solinas,C, AU - Corpino,M, AU - Maccioni,R, AU - Pelosi,U, PY - 2010/9/15/entrez PY - 2010/9/15/pubmed PY - 2011/2/8/medline SP - 76 EP - 9 JF - The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians JO - J. Matern. Fetal. Neonatal. Med. VL - 23 Suppl 3 N2 - Cow's milk protein allergy (CMPA) affects 2-7.5% of children; persistence in adulthood is uncommon since a tolerance develops in 51% of cases within 2 years and 80% within 3-4 years. CMPA is an immunological reaction to one or more milk proteins: α-lactalbumin, β-lactoglobulin, casein, IgE or non-IgE associated, responsible of immediate or late onset symptoms. The suspicion of CMPA is based on detailed family and medical history, skin test, patch test, laboratory test, an elimination diet and food challenge. The general treatment for CMPA is dietary: elimination of cow's milk protein and introduction of extensively hydrolyzed whey or casein formula, amino acid formula, and soy formula. Extensively hydrolyzed whey or casein formula is recommended as first choice for infants in mild or moderate reactions, amino acid formula in severe CMPA and in cases with poor response to extensively hydrolysed whey or casein formula. SN - 1476-4954 UR - https://www.unboundmedicine.com/medline/citation/20836734/Cow's_milk_protein_allergy_ L2 - http://www.tandfonline.com/doi/full/10.3109/14767058.2010.512103 DB - PRIME DP - Unbound Medicine ER -