Tags

Type your tag names separated by a space and hit enter

Focal pulmonary granuloma caused by Cladophialophora bantiana in a domestic short haired cat.
Med Mycol. 2011 Feb; 49(2):194-7.MM

Abstract

Following a 4-week history of coughing, a 12-year-old cat with a history of insulin-dependent diabetes mellitus was diagnosed with a pulmonary granuloma caused by Cladophialophora bantiana. Thoracic radiographs revealed consolidation of the right caudal lung lobe and cytology confirmed the presence of mycotic pneumonia. Results of clinical investigations showed no evidence of extra-pulmonary infection. A thoracotomy and lung lobe resection was performed. Histological examination of the mass revealed black pigmented fungal hyphae and pyogranulomatous inflammation. Cultures inoculated with portions of these tissues yielded a dark walled fungus consistent with an etiologic agent of phaeohyphomycosis and DNA sequencing confirmed the presence of Cladophialophora bantiana. The cat was treated with itraconazole for 4 weeks post-operatively and then with posaconazole for 7 months but was euthanized 13 months after initial diagnosis due to a hepatocellular carcinoma. On post-mortem examination there was no evidence of recurrent fungal infection. This is the first report of localized pulmonary C. bantiana infection in a cat.

Authors+Show Affiliations

Valentine Charlton Cat Centre, Faculty of Veterinary Science, The University of Sydney, New South Wales. natashia.evans@sydney.edu.auNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

20854228

Citation

Evans, Natashia, et al. "Focal Pulmonary Granuloma Caused By Cladophialophora Bantiana in a Domestic Short Haired Cat." Medical Mycology, vol. 49, no. 2, 2011, pp. 194-7.
Evans N, Gunew M, Marshall R, et al. Focal pulmonary granuloma caused by Cladophialophora bantiana in a domestic short haired cat. Med Mycol. 2011;49(2):194-7.
Evans, N., Gunew, M., Marshall, R., Martin, P., & Barrs, V. (2011). Focal pulmonary granuloma caused by Cladophialophora bantiana in a domestic short haired cat. Medical Mycology, 49(2), 194-7. https://doi.org/10.3109/13693786.2010.519349
Evans N, et al. Focal Pulmonary Granuloma Caused By Cladophialophora Bantiana in a Domestic Short Haired Cat. Med Mycol. 2011;49(2):194-7. PubMed PMID: 20854228.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Focal pulmonary granuloma caused by Cladophialophora bantiana in a domestic short haired cat. AU - Evans,Natashia, AU - Gunew,Marcus, AU - Marshall,Rhett, AU - Martin,Patricia, AU - Barrs,Vanessa, Y1 - 2010/09/21/ PY - 2010/9/22/entrez PY - 2010/9/22/pubmed PY - 2011/4/22/medline SP - 194 EP - 7 JF - Medical mycology JO - Med Mycol VL - 49 IS - 2 N2 - Following a 4-week history of coughing, a 12-year-old cat with a history of insulin-dependent diabetes mellitus was diagnosed with a pulmonary granuloma caused by Cladophialophora bantiana. Thoracic radiographs revealed consolidation of the right caudal lung lobe and cytology confirmed the presence of mycotic pneumonia. Results of clinical investigations showed no evidence of extra-pulmonary infection. A thoracotomy and lung lobe resection was performed. Histological examination of the mass revealed black pigmented fungal hyphae and pyogranulomatous inflammation. Cultures inoculated with portions of these tissues yielded a dark walled fungus consistent with an etiologic agent of phaeohyphomycosis and DNA sequencing confirmed the presence of Cladophialophora bantiana. The cat was treated with itraconazole for 4 weeks post-operatively and then with posaconazole for 7 months but was euthanized 13 months after initial diagnosis due to a hepatocellular carcinoma. On post-mortem examination there was no evidence of recurrent fungal infection. This is the first report of localized pulmonary C. bantiana infection in a cat. SN - 1460-2709 UR - https://www.unboundmedicine.com/medline/citation/20854228/Focal_pulmonary_granuloma_caused_by_Cladophialophora_bantiana_in_a_domestic_short_haired_cat_ L2 - https://academic.oup.com/mmy/article-lookup/doi/10.3109/13693786.2010.519349 DB - PRIME DP - Unbound Medicine ER -