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Effectiveness of seasonal 2008-2009, 2009-2010 and pandemic vaccines, to prevent influenza hospitalizations during the autumn 2009 influenza pandemic wave in Castellón, Spain. A test-negative, hospital-based, case-control study.
Vaccine 2010; 28(47):7460-7V

Abstract

We estimate the impact of the two previous influenza seasonal vaccines and the pandemic vaccine on risk of A (H1N1) 2009 laboratory confirmed hospitalizations during the autumn 2009 pandemic wave in Castellón, Spain. We conducted a test-negative, hospital-based, case-control study. Influenza A (H1N1) 2009 infection was detected in 147 (44%) of 334 patients hospitalized for a presumptive influenza related illness. No effect was observed for the 2008-2009 and 2009-2010 seasonal influenza vaccines. However, the pandemic vaccine was associated with an adjusted vaccine effectiveness of 90% (95% CI, 48-100%). Pandemic vaccines were effective in preventing pandemic influenza associated hospitalizations.

Authors+Show Affiliations

Health Promotion Unit, Centro de Salud Pública, Avda del Mar, 12, 12003 Castellón, Spain. jpuigb@terra.esNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

20875486

Citation

Puig-Barberà, Joan, et al. "Effectiveness of Seasonal 2008-2009, 2009-2010 and Pandemic Vaccines, to Prevent Influenza Hospitalizations During the Autumn 2009 Influenza Pandemic Wave in Castellón, Spain. a Test-negative, Hospital-based, Case-control Study." Vaccine, vol. 28, no. 47, 2010, pp. 7460-7.
Puig-Barberà J, Arnedo-Pena A, Pardo-Serrano F, et al. Effectiveness of seasonal 2008-2009, 2009-2010 and pandemic vaccines, to prevent influenza hospitalizations during the autumn 2009 influenza pandemic wave in Castellón, Spain. A test-negative, hospital-based, case-control study. Vaccine. 2010;28(47):7460-7.
Puig-Barberà, J., Arnedo-Pena, A., Pardo-Serrano, F., Tirado-Balaguer, M. D., Pérez-Vilar, S., Silvestre-Silvestre, E., ... Ruiz-García, M. (2010). Effectiveness of seasonal 2008-2009, 2009-2010 and pandemic vaccines, to prevent influenza hospitalizations during the autumn 2009 influenza pandemic wave in Castellón, Spain. A test-negative, hospital-based, case-control study. Vaccine, 28(47), pp. 7460-7. doi:10.1016/j.vaccine.2010.09.042.
Puig-Barberà J, et al. Effectiveness of Seasonal 2008-2009, 2009-2010 and Pandemic Vaccines, to Prevent Influenza Hospitalizations During the Autumn 2009 Influenza Pandemic Wave in Castellón, Spain. a Test-negative, Hospital-based, Case-control Study. Vaccine. 2010 Nov 3;28(47):7460-7. PubMed PMID: 20875486.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effectiveness of seasonal 2008-2009, 2009-2010 and pandemic vaccines, to prevent influenza hospitalizations during the autumn 2009 influenza pandemic wave in Castellón, Spain. A test-negative, hospital-based, case-control study. AU - Puig-Barberà,Joan, AU - Arnedo-Pena,Alberto, AU - Pardo-Serrano,Francisco, AU - Tirado-Balaguer,María Dolores, AU - Pérez-Vilar,Silvia, AU - Silvestre-Silvestre,Ester, AU - Calvo-Mas,Consuelo, AU - Safont-Adsuara,Lourdes, AU - Ruiz-García,Montserrat, AU - ,, Y1 - 2010/09/25/ PY - 2010/07/20/received PY - 2010/09/02/revised PY - 2010/09/12/accepted PY - 2010/9/30/entrez PY - 2010/9/30/pubmed PY - 2011/1/19/medline SP - 7460 EP - 7 JF - Vaccine JO - Vaccine VL - 28 IS - 47 N2 - We estimate the impact of the two previous influenza seasonal vaccines and the pandemic vaccine on risk of A (H1N1) 2009 laboratory confirmed hospitalizations during the autumn 2009 pandemic wave in Castellón, Spain. We conducted a test-negative, hospital-based, case-control study. Influenza A (H1N1) 2009 infection was detected in 147 (44%) of 334 patients hospitalized for a presumptive influenza related illness. No effect was observed for the 2008-2009 and 2009-2010 seasonal influenza vaccines. However, the pandemic vaccine was associated with an adjusted vaccine effectiveness of 90% (95% CI, 48-100%). Pandemic vaccines were effective in preventing pandemic influenza associated hospitalizations. SN - 1873-2518 UR - https://www.unboundmedicine.com/medline/citation/20875486/Effectiveness_of_seasonal_2008_2009_2009_2010_and_pandemic_vaccines_to_prevent_influenza_hospitalizations_during_the_autumn_2009_influenza_pandemic_wave_in_Castellón_Spain__A_test_negative_hospital_based_case_control_study_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0264-410X(10)01352-6 DB - PRIME DP - Unbound Medicine ER -