Tags

Type your tag names separated by a space and hit enter

Low vegetable intake is strongly associated with venous thromboembolism in Thai population.
Blood Coagul Fibrinolysis 2010; 21(8):758-63BC

Abstract

Recent studies have demonstrated a much higher incidence of venous thromboembolism (VTE) among Asian patients compared with previous studies. This study aims to determine dietary and behavioral factors that may have contributed to this increase. A case-control study was conducted. Cases were objectively confirmed VTE between 2006 and 2009 at King Chulalongkorn Memorial Hospital. Patients with underlying cancer, antiphospholipid syndrome and arterial thrombosis were excluded. Controls were age and sex-matched healthy volunteers. Food consumption was assessed using a food frequency questionnaire modified from the Thailand National Health Examination Survey III previously validated in the Thai population. There were 97 cases and 195 controls. The mean age was 54.6 years and 70% were women. VTE patients consumed significantly less vegetable, fish and spicy food compared with normal individuals with an odds ratio (OR) for venous thrombosis of 3.74 [95% confidence interval (CI) 2.24-6.26, P < 0.001], 2.05 (95% CI 1.24-3.41, P = 0.005) and 2.30 (95% CI 1.29-4.11, P = 0.01), respectively. Additionally, thrombosis was associated with overweight (OR 2.1, 95% CI 1.21-3.62, P = 0.002), obesity (OR 3.1, 95% CI 1.46-6.74, P = 0.001) and estrogen uses (OR 3.7, 95% CI 1.05-13.2, P = 0.02), but not with smoking or lack of exercise. A multivariate analysis showed that low vegetable consumption (OR 3.74, 95% CI 1.85-7.55, P < 0.001), female hormones (OR 5.80, 95% CI 1.51-22.22, P = 0.011) and body mass index (BMI, P = 0.048) were independently associated with VTE. Low vegetable intake, hormonal use and high BMI are the risk factors for noncancer-related VTE in Thai population.

Authors+Show Affiliations

Department of Medicine, Thailand.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20885294

Citation

Bhoopat, Lantarima, et al. "Low Vegetable Intake Is Strongly Associated With Venous Thromboembolism in Thai Population." Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis, vol. 21, no. 8, 2010, pp. 758-63.
Bhoopat L, Rojnuckarin P, Hiransuthikul N, et al. Low vegetable intake is strongly associated with venous thromboembolism in Thai population. Blood Coagul Fibrinolysis. 2010;21(8):758-63.
Bhoopat, L., Rojnuckarin, P., Hiransuthikul, N., & Intragumtornchai, T. (2010). Low vegetable intake is strongly associated with venous thromboembolism in Thai population. Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis, 21(8), pp. 758-63. doi:10.1097/MBC.0b013e3283403537.
Bhoopat L, et al. Low Vegetable Intake Is Strongly Associated With Venous Thromboembolism in Thai Population. Blood Coagul Fibrinolysis. 2010;21(8):758-63. PubMed PMID: 20885294.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Low vegetable intake is strongly associated with venous thromboembolism in Thai population. AU - Bhoopat,Lantarima, AU - Rojnuckarin,Ponlapat, AU - Hiransuthikul,Narin, AU - Intragumtornchai,Tanin, PY - 2010/10/2/entrez PY - 2010/10/5/pubmed PY - 2011/3/18/medline SP - 758 EP - 63 JF - Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis JO - Blood Coagul. Fibrinolysis VL - 21 IS - 8 N2 - Recent studies have demonstrated a much higher incidence of venous thromboembolism (VTE) among Asian patients compared with previous studies. This study aims to determine dietary and behavioral factors that may have contributed to this increase. A case-control study was conducted. Cases were objectively confirmed VTE between 2006 and 2009 at King Chulalongkorn Memorial Hospital. Patients with underlying cancer, antiphospholipid syndrome and arterial thrombosis were excluded. Controls were age and sex-matched healthy volunteers. Food consumption was assessed using a food frequency questionnaire modified from the Thailand National Health Examination Survey III previously validated in the Thai population. There were 97 cases and 195 controls. The mean age was 54.6 years and 70% were women. VTE patients consumed significantly less vegetable, fish and spicy food compared with normal individuals with an odds ratio (OR) for venous thrombosis of 3.74 [95% confidence interval (CI) 2.24-6.26, P < 0.001], 2.05 (95% CI 1.24-3.41, P = 0.005) and 2.30 (95% CI 1.29-4.11, P = 0.01), respectively. Additionally, thrombosis was associated with overweight (OR 2.1, 95% CI 1.21-3.62, P = 0.002), obesity (OR 3.1, 95% CI 1.46-6.74, P = 0.001) and estrogen uses (OR 3.7, 95% CI 1.05-13.2, P = 0.02), but not with smoking or lack of exercise. A multivariate analysis showed that low vegetable consumption (OR 3.74, 95% CI 1.85-7.55, P < 0.001), female hormones (OR 5.80, 95% CI 1.51-22.22, P = 0.011) and body mass index (BMI, P = 0.048) were independently associated with VTE. Low vegetable intake, hormonal use and high BMI are the risk factors for noncancer-related VTE in Thai population. SN - 1473-5733 UR - https://www.unboundmedicine.com/medline/citation/20885294/Low_vegetable_intake_is_strongly_associated_with_venous_thromboembolism_in_Thai_population_ L2 - http://dx.doi.org/10.1097/MBC.0b013e3283403537 DB - PRIME DP - Unbound Medicine ER -