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Mass spectroscopic fingerprinting method for differentiation between Scutellaria lateriflora and the germander (Teucrium canadense and T. chamaedrys) species.
J AOAC Int. 2010 Jul-Aug; 93(4):1148-54.JA

Abstract

Scutellaria lateriflora, commonly known as skullcap, is used as an ingredient in numerous herbal products. However, it has been occasionally adulterated/contaminated with Teucrium canadense and T. chamaedrys, commonly known as germander, which contain hepatotoxic diterpenes. Due to the morphological similarities between the two genera, analytical methodologies to distinguish authentic S. lateriflora from the Teucrium species are needed to ensure public safety. In this study, a direct-injection electrospray ionization/MS method was used to generate spectral fingerprints of extracts from 21 skullcap and germander samples at a rate of 90 s/sample. MS fingerprints were analyzed by principal component analysis. The newly developed method offers a rapid and easy way to differentiate between skullcap and germander samples.

Authors+Show Affiliations

U.S. Department of Agriculture, Food Composition Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, Beltsville, MD, USA. pei.chen@ars.usda.govNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Intramural
Research Support, U.S. Gov't, Non-P.H.S.

Language

eng

PubMed ID

20922946

Citation

Chen, Pei, et al. "Mass Spectroscopic Fingerprinting Method for Differentiation Between Scutellaria Lateriflora and the Germander (Teucrium Canadense and T. Chamaedrys) Species." Journal of AOAC International, vol. 93, no. 4, 2010, pp. 1148-54.
Chen P, Lin LZ, Harnly JM. Mass spectroscopic fingerprinting method for differentiation between Scutellaria lateriflora and the germander (Teucrium canadense and T. chamaedrys) species. J AOAC Int. 2010;93(4):1148-54.
Chen, P., Lin, L. Z., & Harnly, J. M. (2010). Mass spectroscopic fingerprinting method for differentiation between Scutellaria lateriflora and the germander (Teucrium canadense and T. chamaedrys) species. Journal of AOAC International, 93(4), 1148-54.
Chen P, Lin LZ, Harnly JM. Mass Spectroscopic Fingerprinting Method for Differentiation Between Scutellaria Lateriflora and the Germander (Teucrium Canadense and T. Chamaedrys) Species. J AOAC Int. 2010 Jul-Aug;93(4):1148-54. PubMed PMID: 20922946.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Mass spectroscopic fingerprinting method for differentiation between Scutellaria lateriflora and the germander (Teucrium canadense and T. chamaedrys) species. AU - Chen,Pei, AU - Lin,Long-Ze, AU - Harnly,James M, PY - 2010/10/7/entrez PY - 2010/10/7/pubmed PY - 2010/10/29/medline SP - 1148 EP - 54 JF - Journal of AOAC International JO - J AOAC Int VL - 93 IS - 4 N2 - Scutellaria lateriflora, commonly known as skullcap, is used as an ingredient in numerous herbal products. However, it has been occasionally adulterated/contaminated with Teucrium canadense and T. chamaedrys, commonly known as germander, which contain hepatotoxic diterpenes. Due to the morphological similarities between the two genera, analytical methodologies to distinguish authentic S. lateriflora from the Teucrium species are needed to ensure public safety. In this study, a direct-injection electrospray ionization/MS method was used to generate spectral fingerprints of extracts from 21 skullcap and germander samples at a rate of 90 s/sample. MS fingerprints were analyzed by principal component analysis. The newly developed method offers a rapid and easy way to differentiate between skullcap and germander samples. SN - 1060-3271 UR - https://www.unboundmedicine.com/medline/citation/20922946/Mass_spectroscopic_fingerprinting_method_for_differentiation_between_Scutellaria_lateriflora_and_the_germander__Teucrium_canadense_and_T__chamaedrys__species_ L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20922946/ DB - PRIME DP - Unbound Medicine ER -