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Three new dammarane-type triterpene saponins from the leaves of Panax ginseng C.A. Meyer.
J Asian Nat Prod Res. 2010 Oct; 12(10):865-73.JA

Abstract

Three new dammarane-type triterpene ginsenosides, together with six known ginsenosides, were isolated from the leaves of Panax ginseng C.A. Meyer. The new saponins were named as ginsenoside Rh₁₁, ginsenoside Rh₁₂, and ginsenoside Rh₁₃. Their structures were elucidated as (20S)-3β,6α,12β,20-tetrahydroxydammara-25-ene-24-one 20-O-β-d-glucopyranoside (1), (20S)-3β,12β,20,24,25-pentahydroxydammarane 20-O-β-d-glucopyranoside (2), and (20S,23E)-3β,12β,20,25-tetrahydroxydammara-23-ene 20-O-β-d-glucopyranoside (3) on the basis of 1D and 2D NMR experiments and mass spectra. The known ginsenosides were identified as ginsenoside M(₇cd), ginsenoside Rg₆, ginsenoside Rb₃, gypenoside XVII, gypenoside IX, and 20-(E)-ginsenoside F₄.

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Authors+Show Affiliations

Liu GY
Department of Analytical Chemistry, College of Chemistry, Jilin University, Changchun, China.
Li XW
No affiliation info available
Wang NB
No affiliation info available
Zhou HY
No affiliation info available
Wei W
No affiliation info available
Gui MY
No affiliation info available
Yang B
No affiliation info available
Jin YR
No affiliation info available

MeSH

Drugs, Chinese HerbalGinsenosidesMolecular StructureNuclear Magnetic Resonance, BiomolecularPanaxPlant LeavesSaponinsStereoisomerismTriterpenes

Pub Type(s)

Journal Article

Language

eng

PubMed ID

20924900

Citation

Liu, Gui-Ying, et al. "Three New Dammarane-type Triterpene Saponins From the Leaves of Panax Ginseng C.A. Meyer." Journal of Asian Natural Products Research, vol. 12, no. 10, 2010, pp. 865-73.
Liu GY, Li XW, Wang NB, et al. Three new dammarane-type triterpene saponins from the leaves of Panax ginseng C.A. Meyer. J Asian Nat Prod Res. 2010;12(10):865-73.
Liu, G. Y., Li, X. W., Wang, N. B., Zhou, H. Y., Wei, W., Gui, M. Y., Yang, B., & Jin, Y. R. (2010). Three new dammarane-type triterpene saponins from the leaves of Panax ginseng C.A. Meyer. Journal of Asian Natural Products Research, 12(10), 865-73. https://doi.org/10.1080/10286020.2010.508035
Liu GY, et al. Three New Dammarane-type Triterpene Saponins From the Leaves of Panax Ginseng C.A. Meyer. J Asian Nat Prod Res. 2010;12(10):865-73. PubMed PMID: 20924900.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Three new dammarane-type triterpene saponins from the leaves of Panax ginseng C.A. Meyer. AU - Liu,Gui-Ying, AU - Li,Xu-Wen, AU - Wang,Nian-Bin, AU - Zhou,Hong-Yu, AU - Wei,Wei, AU - Gui,Ming-Yu, AU - Yang,Bin, AU - Jin,Yong-Ri, PY - 2010/10/7/entrez PY - 2010/10/7/pubmed PY - 2010/10/27/medline SP - 865 EP - 73 JF - Journal of Asian natural products research JO - J Asian Nat Prod Res VL - 12 IS - 10 N2 - Three new dammarane-type triterpene ginsenosides, together with six known ginsenosides, were isolated from the leaves of Panax ginseng C.A. Meyer. The new saponins were named as ginsenoside Rh₁₁, ginsenoside Rh₁₂, and ginsenoside Rh₁₃. Their structures were elucidated as (20S)-3β,6α,12β,20-tetrahydroxydammara-25-ene-24-one 20-O-β-d-glucopyranoside (1), (20S)-3β,12β,20,24,25-pentahydroxydammarane 20-O-β-d-glucopyranoside (2), and (20S,23E)-3β,12β,20,25-tetrahydroxydammara-23-ene 20-O-β-d-glucopyranoside (3) on the basis of 1D and 2D NMR experiments and mass spectra. The known ginsenosides were identified as ginsenoside M(₇cd), ginsenoside Rg₆, ginsenoside Rb₃, gypenoside XVII, gypenoside IX, and 20-(E)-ginsenoside F₄. SN - 1477-2213 UR - https://www.unboundmedicine.com/medline/citation/20924900/Three_new_dammarane_type_triterpene_saponins_from_the_leaves_of_Panax_ginseng_C_A__Meyer_ L2 - https://www.tandfonline.com/doi/full/10.1080/10286020.2010.508035 DB - PRIME DP - Unbound Medicine ER -