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Managing spasticity with drugs.
Eur J Phys Rehabil Med. 2010 Sep; 46(3):401-10.EJ

Abstract

Spasticity is a common symptom observed after pyramidal system lesion. The treatment of spasticity has considerably changed during last years, notably with the generalization of Botulinum toxin use. However, the treatment of spasticity should consider all therapeutic possibility in accordance with patient status and objective. Drugs are only a part of the treatment and physical therapy must always be used. Others treatments such as surgery, orthosis, occupational therapy must also be discussed individually. Several guidelines are now available for Botulinum toxin treatment but only the French guidelines consider all drug therapies. This review addresses the different drugs commonly used on the basis of an extensive review of literature. Some facts are clearly established by randomized controlled trials but a certain number of questions remains unclear and only clinical experience and consensus can guide injectors.

Authors+Show Affiliations

Physical Medicine and Rehabilitation Department, AP-HP, GH Bichat, University Paris7, Paris, France. olivier.simon@bch.aphp.frNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

20927006

Citation

Simon, O, and A P. Yelnik. "Managing Spasticity With Drugs." European Journal of Physical and Rehabilitation Medicine, vol. 46, no. 3, 2010, pp. 401-10.
Simon O, Yelnik AP. Managing spasticity with drugs. Eur J Phys Rehabil Med. 2010;46(3):401-10.
Simon, O., & Yelnik, A. P. (2010). Managing spasticity with drugs. European Journal of Physical and Rehabilitation Medicine, 46(3), 401-10.
Simon O, Yelnik AP. Managing Spasticity With Drugs. Eur J Phys Rehabil Med. 2010;46(3):401-10. PubMed PMID: 20927006.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Managing spasticity with drugs. AU - Simon,O, AU - Yelnik,A P, PY - 2010/10/8/entrez PY - 2010/10/12/pubmed PY - 2011/2/1/medline SP - 401 EP - 10 JF - European journal of physical and rehabilitation medicine JO - Eur J Phys Rehabil Med VL - 46 IS - 3 N2 - Spasticity is a common symptom observed after pyramidal system lesion. The treatment of spasticity has considerably changed during last years, notably with the generalization of Botulinum toxin use. However, the treatment of spasticity should consider all therapeutic possibility in accordance with patient status and objective. Drugs are only a part of the treatment and physical therapy must always be used. Others treatments such as surgery, orthosis, occupational therapy must also be discussed individually. Several guidelines are now available for Botulinum toxin treatment but only the French guidelines consider all drug therapies. This review addresses the different drugs commonly used on the basis of an extensive review of literature. Some facts are clearly established by randomized controlled trials but a certain number of questions remains unclear and only clinical experience and consensus can guide injectors. SN - 1973-9095 UR - https://www.unboundmedicine.com/medline/citation/20927006/Managing_spasticity_with_drugs_ L2 - http://www.minervamedica.it/index2.t?show=R33Y2010N03A0401 DB - PRIME DP - Unbound Medicine ER -