TY - JOUR T1 - Influenza vaccination for healthcare workers who work with the elderly: systematic review. AU - Thomas,Roger E, AU - Jefferson,Tom, AU - Lasserson,Toby J, Y1 - 2010/11/18/ PY - 2010/05/09/received PY - 2010/09/01/revised PY - 2010/09/24/accepted PY - 2010/10/13/entrez PY - 2010/10/13/pubmed PY - 2011/3/11/medline SP - 344 EP - 56 JF - Vaccine JO - Vaccine VL - 29 IS - 2 N2 - AIM: To identify studies of influenza vaccination of HCWs and influenza in elderly residents in long-term care facilities. SCOPE: We searched seven electronic databases for randomised controlled trials (RCTs) and non-RCTs. Two reviewers independently extracted data and assessed trial quality. CONCLUSIONS: The key outcomes are serologically proven influenza, pneumonia, and deaths from pneumonia, and pooled data from three C-RCTs showed no effect. Pooled data from three C-RCTs showed lower resident all-cause mortality, but as influenza constituted less than 10% of all deaths even in epidemic years we question the appropriateness of this outcome measure. Pooled data from three C-RCTs showed vaccination of HCWs reduced ILI and data from one C-RCT that HCW vaccination reduced GP consultations for ILI, but as influenza constitutes less than 25% of ILI and we did not show that HCW influenza vaccination reduced serologically proven influenza we question whether this effect is due to confounding. SN - 1873-2518 UR - https://www.unboundmedicine.com/medline/citation/20937313/Influenza_vaccination_for_healthcare_workers_who_work_with_the_elderly:_systematic_review_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0264-410X(10)01427-1 DB - PRIME DP - Unbound Medicine ER -