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A new antioxidant xanthone from the pericarp of Garcinia mangostana Linn.
Nat Prod Res. 2010 Oct; 24(17):1664-70.NP

Abstract

The air-dried fruit hulls of Garcinia mangostana Linn. were extracted with 85% ethanol. Furthermore, a new xanthone, 1,3,6-trihydroxy-2,5-bis(3-methylbut-2-enyl)-6',6'-dimethyl-4',5'-dihydropyrano[2',3':7,8]xanthone, along with five known xanthones related to their antioxidant activity was purified by silica gel column chromatography and then identified using spectroscopic methods (1D and 2D NMR, MS). The antioxidant activities were evaluated using 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging capability. An activity-guided isolation and purification process were used to identify the components, showing the strong DPPH radical-scavenging activity of G. mangostana.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Zhao Y
College of Chinese Medicinal Materials, Jilin Agricultural University, ChangChun 130118, China.
Liu JP
No affiliation info available
Lu D
No affiliation info available
Li PY
No affiliation info available
Zhang LX
No affiliation info available

MeSH

AntioxidantsBiphenyl CompoundsFree Radical ScavengersGarciniaMagnetic Resonance SpectroscopyPicratesSpectrometry, Mass, Electrospray IonizationXanthones

Pub Type(s)

Journal Article

Language

eng

PubMed ID

20954095

Citation

Zhao, Yan, et al. "A New Antioxidant Xanthone From the Pericarp of Garcinia Mangostana Linn." Natural Product Research, vol. 24, no. 17, 2010, pp. 1664-70.
Zhao Y, Liu JP, Lu D, et al. A new antioxidant xanthone from the pericarp of Garcinia mangostana Linn. Nat Prod Res. 2010;24(17):1664-70.
Zhao, Y., Liu, J. P., Lu, D., Li, P. Y., & Zhang, L. X. (2010). A new antioxidant xanthone from the pericarp of Garcinia mangostana Linn. Natural Product Research, 24(17), 1664-70. https://doi.org/10.1080/14786419.2010.499539
Zhao Y, et al. A New Antioxidant Xanthone From the Pericarp of Garcinia Mangostana Linn. Nat Prod Res. 2010;24(17):1664-70. PubMed PMID: 20954095.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A new antioxidant xanthone from the pericarp of Garcinia mangostana Linn. AU - Zhao,Yan, AU - Liu,Jin-Ping, AU - Lu,Dan, AU - Li,Ping-Ya, AU - Zhang,Lian-Xue, PY - 2010/10/19/entrez PY - 2010/10/19/pubmed PY - 2011/2/11/medline SP - 1664 EP - 70 JF - Natural product research JO - Nat Prod Res VL - 24 IS - 17 N2 - The air-dried fruit hulls of Garcinia mangostana Linn. were extracted with 85% ethanol. Furthermore, a new xanthone, 1,3,6-trihydroxy-2,5-bis(3-methylbut-2-enyl)-6',6'-dimethyl-4',5'-dihydropyrano[2',3':7,8]xanthone, along with five known xanthones related to their antioxidant activity was purified by silica gel column chromatography and then identified using spectroscopic methods (1D and 2D NMR, MS). The antioxidant activities were evaluated using 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging capability. An activity-guided isolation and purification process were used to identify the components, showing the strong DPPH radical-scavenging activity of G. mangostana. SN - 1478-6427 UR - https://www.unboundmedicine.com/medline/citation/20954095/A_new_antioxidant_xanthone_from_the_pericarp_of_Garcinia_mangostana_Linn_ DB - PRIME DP - Unbound Medicine ER -