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Comparison of a chloral hydrate/hydroxyzine combination with and without meperidine in the sedation of pediatric dental patients.
Pediatr Dent 1990 Sep-Oct; 12(5):288-91PD

Abstract

The purpose of this study was to compare the effectiveness of a chloral hydrate/hydroxyzine combination with and without meperidine in the sedation of pediatric dental patients. Twenty children were given 40 mg/kg chloral hydrate and 25 mg hydroxyzine, and 20 children were given 40 mg/kg chloral hydrate and 25 mg hydroxyzine and 0.5 mg/kg meperidine. All children were between the ages of 24 and 60 months and all medications were given orally 1 hr before treatment. The children received 50% nitrous oxide for the entire procedure. All children were restrained in a Papoose Board. The patients were videotaped and their behavior was rated by two independent pediatric dentists using the Houpt Scale. The independent evaluators did not know which sedation regimen had been used. They rated success of the sedations by degree of sleep, crying, body movements, and overall behavior. Oxygen saturation of arterial blood, and heart rate also were measured. The vital signs were consistent for the two groups. There was no significant difference in the effectiveness of the two drug regimens.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

2095539

Citation

Poorman, T L., et al. "Comparison of a Chloral Hydrate/hydroxyzine Combination With and Without Meperidine in the Sedation of Pediatric Dental Patients." Pediatric Dentistry, vol. 12, no. 5, 1990, pp. 288-91.
Poorman TL, Farrington FH, Mourino AP. Comparison of a chloral hydrate/hydroxyzine combination with and without meperidine in the sedation of pediatric dental patients. Pediatr Dent. 1990;12(5):288-91.
Poorman, T. L., Farrington, F. H., & Mourino, A. P. (1990). Comparison of a chloral hydrate/hydroxyzine combination with and without meperidine in the sedation of pediatric dental patients. Pediatric Dentistry, 12(5), pp. 288-91.
Poorman TL, Farrington FH, Mourino AP. Comparison of a Chloral Hydrate/hydroxyzine Combination With and Without Meperidine in the Sedation of Pediatric Dental Patients. Pediatr Dent. 1990;12(5):288-91. PubMed PMID: 2095539.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparison of a chloral hydrate/hydroxyzine combination with and without meperidine in the sedation of pediatric dental patients. AU - Poorman,T L, AU - Farrington,F H, AU - Mourino,A P, PY - 1990/9/1/pubmed PY - 1990/9/1/medline PY - 1990/9/1/entrez SP - 288 EP - 91 JF - Pediatric dentistry JO - Pediatr Dent VL - 12 IS - 5 N2 - The purpose of this study was to compare the effectiveness of a chloral hydrate/hydroxyzine combination with and without meperidine in the sedation of pediatric dental patients. Twenty children were given 40 mg/kg chloral hydrate and 25 mg hydroxyzine, and 20 children were given 40 mg/kg chloral hydrate and 25 mg hydroxyzine and 0.5 mg/kg meperidine. All children were between the ages of 24 and 60 months and all medications were given orally 1 hr before treatment. The children received 50% nitrous oxide for the entire procedure. All children were restrained in a Papoose Board. The patients were videotaped and their behavior was rated by two independent pediatric dentists using the Houpt Scale. The independent evaluators did not know which sedation regimen had been used. They rated success of the sedations by degree of sleep, crying, body movements, and overall behavior. Oxygen saturation of arterial blood, and heart rate also were measured. The vital signs were consistent for the two groups. There was no significant difference in the effectiveness of the two drug regimens. SN - 0164-1263 UR - https://www.unboundmedicine.com/medline/citation/2095539/Comparison_of_a_chloral_hydrate/hydroxyzine_combination_with_and_without_meperidine_in_the_sedation_of_pediatric_dental_patients_ DB - PRIME DP - Unbound Medicine ER -