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Performance of extracorporeally adjustable ventricular assist device inflow cannula.
Ann Thorac Surg. 2010 Nov; 90(5):1682-7.AT

Abstract

PURPOSE

This study evaluated the feasibility and efficacy of a newly developed adjustable left ventricular assist device inflow cannula in a short-term calf model.

DESCRIPTION

In this inflow cannula, the angle between the cannula body and the inflow cannula tip can be altered extracorporeally by manipulating 2 externalized cables connected to the cannula. The cannula tip is adjustable in any plane to a maximum of ±15 degrees.

EVALUATION

After initial prototyping in 4 calf cadavers, a Cleveland Heart left ventricular assist device was implanted with the adjustable inflow cannula placed in the left ventricular apex and the outlet to the descending aorta. Under hypovolemic conditions, the angle of the cannula tip could be changed to induce varying degrees of ventricular suction and then eliminate it, as evidenced by recorded pump and native left ventricular flows. Epicardial echocardiography and fluoroscopy in the closed-chest condition documented extracorporeal adjustments of the inflow cannula position.

CONCLUSIONS

This extracorporeally adjustable inflow cannula was effective in preventing or controlling left ventricular suction.

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Authors+Show Affiliations

Shiose A
Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA.
Kim HI
No affiliation info available
Takaseya T
No affiliation info available
Kobayashi M
No affiliation info available
Fujiki M
No affiliation info available
Chen JF
No affiliation info available
Klatte R
No affiliation info available
Gao S
No affiliation info available
Massiello AL
No affiliation info available
Saeed D
No affiliation info available
Fukamachi K
No affiliation info available

MeSH

AnimalsCatheterizationCattleHeart-Assist DevicesVentricular Function, Left

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20971290

Citation

Shiose, Akira, et al. "Performance of Extracorporeally Adjustable Ventricular Assist Device Inflow Cannula." The Annals of Thoracic Surgery, vol. 90, no. 5, 2010, pp. 1682-7.
Shiose A, Kim HI, Takaseya T, et al. Performance of extracorporeally adjustable ventricular assist device inflow cannula. Ann Thorac Surg. 2010;90(5):1682-7.
Shiose, A., Kim, H. I., Takaseya, T., Kobayashi, M., Fujiki, M., Chen, J. F., Klatte, R., Gao, S., Massiello, A. L., Saeed, D., & Fukamachi, K. (2010). Performance of extracorporeally adjustable ventricular assist device inflow cannula. The Annals of Thoracic Surgery, 90(5), 1682-7. https://doi.org/10.1016/j.athoracsur.2010.06.081
Shiose A, et al. Performance of Extracorporeally Adjustable Ventricular Assist Device Inflow Cannula. Ann Thorac Surg. 2010;90(5):1682-7. PubMed PMID: 20971290.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Performance of extracorporeally adjustable ventricular assist device inflow cannula. AU - Shiose,Akira, AU - Kim,Hyun-Il, AU - Takaseya,Tohru, AU - Kobayashi,Mariko, AU - Fujiki,Masako, AU - Chen,Ji-Feng, AU - Klatte,Ryan, AU - Gao,Shengqiang, AU - Massiello,Alex L, AU - Saeed,Diyar, AU - Fukamachi,Kiyotaka, PY - 2010/04/12/received PY - 2010/06/11/revised PY - 2010/06/14/accepted PY - 2010/10/26/entrez PY - 2010/10/26/pubmed PY - 2010/11/11/medline SP - 1682 EP - 7 JF - The Annals of thoracic surgery JO - Ann Thorac Surg VL - 90 IS - 5 N2 - PURPOSE: This study evaluated the feasibility and efficacy of a newly developed adjustable left ventricular assist device inflow cannula in a short-term calf model. DESCRIPTION: In this inflow cannula, the angle between the cannula body and the inflow cannula tip can be altered extracorporeally by manipulating 2 externalized cables connected to the cannula. The cannula tip is adjustable in any plane to a maximum of ±15 degrees. EVALUATION: After initial prototyping in 4 calf cadavers, a Cleveland Heart left ventricular assist device was implanted with the adjustable inflow cannula placed in the left ventricular apex and the outlet to the descending aorta. Under hypovolemic conditions, the angle of the cannula tip could be changed to induce varying degrees of ventricular suction and then eliminate it, as evidenced by recorded pump and native left ventricular flows. Epicardial echocardiography and fluoroscopy in the closed-chest condition documented extracorporeal adjustments of the inflow cannula position. CONCLUSIONS: This extracorporeally adjustable inflow cannula was effective in preventing or controlling left ventricular suction. SN - 1552-6259 UR - https://www.unboundmedicine.com/medline/citation/20971290/Performance_of_extracorporeally_adjustable_ventricular_assist_device_inflow_cannula_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0003-4975(10)01450-5 DB - PRIME DP - Unbound Medicine ER -