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Progression of null or mild lower urinary tract symptoms indicative of benign prostatic hyperplasia after 2 years of follow-up in non-treated men aged 40 years or older.
Urology. 2011 Mar; 77(3):693-8.U

Abstract

OBJECTIVES

After screening men aged 40 years or older for lower urinary tract symptoms (LUTS) indicative of benign prostatic hyperplasia over the years 1999 to 2000, non-treated men with an initial International Prostate Symptoms Score (I-PSS) equal to or lower than 2 were assessed 2 years later for symptom progression.

METHODS

A cross-sectional study was conducted in 1999 on 1804 men aged 40 years or older who were living in Madrid. In a telephone interview sociodemographic information was requested and LUTS assessed using the I-PSS. Of 975 men with no LUTS or lower than 2 in this baseline survey, 463 were re-interviewed in 2001. The dependent variable was the change from null/mild to moderate/severe LUTS produced over 2 years.

RESULTS

Over the 2-year period, the mean increase in I-PSS score was 2.20 (95% CI, 1.89-2.51). The cumulative incidence of progression from asymptomatic/mild to moderate/severe disease was 9.94% (95% CI, 7.53-13.00). In the multivariate logistic regression model men who lived in a rural setting (OR, 2.70; P = .01) and armed forces, qualified agriculture and fishing workers (OR, 4.11; P = .05) were independently associated with progression. Age and alcohol intake were also found to interact; intake of 0.01-25.99 g/day in men older than 50 years (OR, 0.28; P = .008) was related to a lower frequency of progression than the same alcohol intake in men younger than 50 years (OR, 2.03; P = .380).

CONCLUSIONS

After the 2-year period, the incidence of symptom progression was 10% in men aged 40 years or older with an initial I-PSS equal to or lower than 2.

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Authors+Show Affiliations

Moreno Sierra J
Department of Urology, Research Unit, Hospital Clínico, San Carlos, Madrid, Spain. dr_jmoreno@hotmail.com
Fernandez Pérez C
No affiliation info available
Cano Escudero S
No affiliation info available
Fuentes Ferrer M
No affiliation info available
Barreales Tolosa L
No affiliation info available
Silmi Moyano A
No affiliation info available

MeSH

AdultAgedDisease ProgressionHumansMaleMiddle AgedProstatic HyperplasiaSocioeconomic FactorsSpainUrination Disorders

Pub Type(s)

Journal Article

Language

eng

PubMed ID

20974488

Citation

Moreno Sierra, Jesús, et al. "Progression of Null or Mild Lower Urinary Tract Symptoms Indicative of Benign Prostatic Hyperplasia After 2 Years of Follow-up in Non-treated Men Aged 40 Years or Older." Urology, vol. 77, no. 3, 2011, pp. 693-8.
Moreno Sierra J, Fernandez Pérez C, Cano Escudero S, et al. Progression of null or mild lower urinary tract symptoms indicative of benign prostatic hyperplasia after 2 years of follow-up in non-treated men aged 40 years or older. Urology. 2011;77(3):693-8.
Moreno Sierra, J., Fernandez Pérez, C., Cano Escudero, S., Fuentes Ferrer, M., Barreales Tolosa, L., & Silmi Moyano, A. (2011). Progression of null or mild lower urinary tract symptoms indicative of benign prostatic hyperplasia after 2 years of follow-up in non-treated men aged 40 years or older. Urology, 77(3), 693-8. https://doi.org/10.1016/j.urology.2010.07.459
Moreno Sierra J, et al. Progression of Null or Mild Lower Urinary Tract Symptoms Indicative of Benign Prostatic Hyperplasia After 2 Years of Follow-up in Non-treated Men Aged 40 Years or Older. Urology. 2011;77(3):693-8. PubMed PMID: 20974488.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Progression of null or mild lower urinary tract symptoms indicative of benign prostatic hyperplasia after 2 years of follow-up in non-treated men aged 40 years or older. AU - Moreno Sierra,Jesús, AU - Fernandez Pérez,Cristina, AU - Cano Escudero,Sara, AU - Fuentes Ferrer,Manuel, AU - Barreales Tolosa,Laura, AU - Silmi Moyano,Angel, Y1 - 2010/10/25/ PY - 2010/04/12/received PY - 2010/06/30/revised PY - 2010/07/09/accepted PY - 2010/10/27/entrez PY - 2010/10/27/pubmed PY - 2011/5/12/medline SP - 693 EP - 8 JF - Urology JO - Urology VL - 77 IS - 3 N2 - OBJECTIVES: After screening men aged 40 years or older for lower urinary tract symptoms (LUTS) indicative of benign prostatic hyperplasia over the years 1999 to 2000, non-treated men with an initial International Prostate Symptoms Score (I-PSS) equal to or lower than 2 were assessed 2 years later for symptom progression. METHODS: A cross-sectional study was conducted in 1999 on 1804 men aged 40 years or older who were living in Madrid. In a telephone interview sociodemographic information was requested and LUTS assessed using the I-PSS. Of 975 men with no LUTS or lower than 2 in this baseline survey, 463 were re-interviewed in 2001. The dependent variable was the change from null/mild to moderate/severe LUTS produced over 2 years. RESULTS: Over the 2-year period, the mean increase in I-PSS score was 2.20 (95% CI, 1.89-2.51). The cumulative incidence of progression from asymptomatic/mild to moderate/severe disease was 9.94% (95% CI, 7.53-13.00). In the multivariate logistic regression model men who lived in a rural setting (OR, 2.70; P = .01) and armed forces, qualified agriculture and fishing workers (OR, 4.11; P = .05) were independently associated with progression. Age and alcohol intake were also found to interact; intake of 0.01-25.99 g/day in men older than 50 years (OR, 0.28; P = .008) was related to a lower frequency of progression than the same alcohol intake in men younger than 50 years (OR, 2.03; P = .380). CONCLUSIONS: After the 2-year period, the incidence of symptom progression was 10% in men aged 40 years or older with an initial I-PSS equal to or lower than 2. SN - 1527-9995 UR - https://www.unboundmedicine.com/medline/citation/20974488/Progression_of_null_or_mild_lower_urinary_tract_symptoms_indicative_of_benign_prostatic_hyperplasia_after_2_years_of_follow_up_in_non_treated_men_aged_40_years_or_older_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0090-4295(10)01447-0 DB - PRIME DP - Unbound Medicine ER -