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New phenylpropanoids and in vitro α-glucosidase inhibitors from Balanophora japonica.
Planta Med. 2011 Mar; 77(5):477-81.PM

Abstract

Five new phenylpropanoids, named balajaponins A-E (1-5), were isolated from Balanophora japonica, along with 24 known compounds. Among them, three hydrolysable tannins (6-8) showed specific in vitro α-glucosidase inhibition, with IC₅₀ values in the range of 1-4 µM. Kinetic analysis revealed that they all acted in a noncompetitive mode.

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Authors+Show Affiliations

Zhou T
State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, P. R. China.
Zhang XH
No affiliation info available
Zhang SW
No affiliation info available
Liu SS
No affiliation info available
Xuan LJ
No affiliation info available

MeSH

BalanophoraceaeEnzyme InhibitorsGlycoside Hydrolase InhibitorsHydrolyzable TanninsInhibitory Concentration 50KineticsMagnetic Resonance SpectroscopyMolecular StructurePhenylpropionatesPlant Extractsalpha-Glucosidases

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20979022

Citation

Zhou, Tong, et al. "New Phenylpropanoids and in Vitro Α-glucosidase Inhibitors From Balanophora Japonica." Planta Medica, vol. 77, no. 5, 2011, pp. 477-81.
Zhou T, Zhang XH, Zhang SW, et al. New phenylpropanoids and in vitro α-glucosidase inhibitors from Balanophora japonica. Planta Med. 2011;77(5):477-81.
Zhou, T., Zhang, X. H., Zhang, S. W., Liu, S. S., & Xuan, L. J. (2011). New phenylpropanoids and in vitro α-glucosidase inhibitors from Balanophora japonica. Planta Medica, 77(5), 477-81. https://doi.org/10.1055/s-0030-1250464
Zhou T, et al. New Phenylpropanoids and in Vitro Α-glucosidase Inhibitors From Balanophora Japonica. Planta Med. 2011;77(5):477-81. PubMed PMID: 20979022.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - New phenylpropanoids and in vitro α-glucosidase inhibitors from Balanophora japonica. AU - Zhou,Tong, AU - Zhang,Xiao-hui, AU - Zhang,Shu-wei, AU - Liu,Shan-shan, AU - Xuan,Li-jiang, Y1 - 2010/10/26/ PY - 2010/10/28/entrez PY - 2010/10/28/pubmed PY - 2012/7/27/medline SP - 477 EP - 81 JF - Planta medica JO - Planta Med VL - 77 IS - 5 N2 - Five new phenylpropanoids, named balajaponins A-E (1-5), were isolated from Balanophora japonica, along with 24 known compounds. Among them, three hydrolysable tannins (6-8) showed specific in vitro α-glucosidase inhibition, with IC₅₀ values in the range of 1-4 µM. Kinetic analysis revealed that they all acted in a noncompetitive mode. SN - 1439-0221 UR - https://www.unboundmedicine.com/medline/citation/20979022/New_phenylpropanoids_and_in_vitro_α_glucosidase_inhibitors_from_Balanophora_japonica_ L2 - http://www.thieme-connect.com/DOI/DOI?10.1055/s-0030-1250464 DB - PRIME DP - Unbound Medicine ER -