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Managing irritability and aggression in autism spectrum disorders in children and adolescents.
Dev Disabil Res Rev. 2010; 16(3):258-64.DD

Abstract

Children with autism and autism spectrum disorders have a high rate of irritability and aggressive symptoms. In one study up to 20% of children with autism have symptoms of irritability and aggression including aggression, severe tantrums, and deliberate self injurious behavior (Lecavalier [2006] J. Autism Dev. Disord. 36:1101-1114.). These symptoms can lead to impairment and distress in both home and school settings. Medications to treat the irritability will be discussed across categories of antipsychotics, antidepressants, antihypertensive agents, and others. Emphasis will be placed on medications with the most safety and efficacy and FDA approval.

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Authors+Show Affiliations

Robb AS
Department of Psychiatry and Pediatrics, George Washington University Medical Center, Children's National Medical Center, Washington, DC, USA. arobb@cnmc.org

MeSH

AdolescentAggressionAnticonvulsantsAntidepressive AgentsAntihypertensive AgentsAntipsychotic AgentsChildChild Development Disorders, PervasiveChild, PreschoolClinical Trials as TopicHumansIrritable Mood

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

20981764

Citation

Robb, Adelaide S.. "Managing Irritability and Aggression in Autism Spectrum Disorders in Children and Adolescents." Developmental Disabilities Research Reviews, vol. 16, no. 3, 2010, pp. 258-64.
Robb AS. Managing irritability and aggression in autism spectrum disorders in children and adolescents. Dev Disabil Res Rev. 2010;16(3):258-64.
Robb, A. S. (2010). Managing irritability and aggression in autism spectrum disorders in children and adolescents. Developmental Disabilities Research Reviews, 16(3), 258-64. https://doi.org/10.1002/ddrr.118
Robb AS. Managing Irritability and Aggression in Autism Spectrum Disorders in Children and Adolescents. Dev Disabil Res Rev. 2010;16(3):258-64. PubMed PMID: 20981764.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Managing irritability and aggression in autism spectrum disorders in children and adolescents. A1 - Robb,Adelaide S, PY - 2010/10/29/entrez PY - 2010/10/29/pubmed PY - 2011/3/23/medline SP - 258 EP - 64 JF - Developmental disabilities research reviews JO - Dev Disabil Res Rev VL - 16 IS - 3 N2 - Children with autism and autism spectrum disorders have a high rate of irritability and aggressive symptoms. In one study up to 20% of children with autism have symptoms of irritability and aggression including aggression, severe tantrums, and deliberate self injurious behavior (Lecavalier [2006] J. Autism Dev. Disord. 36:1101-1114.). These symptoms can lead to impairment and distress in both home and school settings. Medications to treat the irritability will be discussed across categories of antipsychotics, antidepressants, antihypertensive agents, and others. Emphasis will be placed on medications with the most safety and efficacy and FDA approval. SN - 1940-5529 UR - https://www.unboundmedicine.com/medline/citation/20981764/Managing_irritability_and_aggression_in_autism_spectrum_disorders_in_children_and_adolescents_ L2 - https://doi.org/10.1002/ddrr.118 DB - PRIME DP - Unbound Medicine ER -