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Rhinovirus species and their clinical presentation among different risk groups of non-hospitalized patients.
J Med Virol. 2010 Dec; 82(12):2110-5.JM

Abstract

Infections caused by Human Rhinoviruses (HRVs) account for 25-50% of respiratory illnesses among individuals presenting influenza-like illness (ILI). HRVs could be classified in at least three species: HRV-A, HRV-B, and HRV-C. The HRV-C species has frequently been described among children and has led to severe illness resulting in hospitalization; however, the occurrence among adults is unknown. The aim of this study was to assess the clinical presentation and species distribution of HRV infections in different populations during 2001-2008. A total of 770 samples were collected. Subjects consisted of 136 adults from the general community and 207 health-care workers (2001-2003), 232 renal-transplanted outpatients (2002-2004), 70 children with congenital heart disease (2005) and 125 children from a day-care center (2008). Amplification of HRV genes was performed by reverse transcriptase-polymerase chain reaction (RT-PCR) and followed by sequencing and phylogenetic analysis. HRV was detected in 27.4% of samples (211/770), with 72 children (36.9%) and 139 adults infected (24.2%). A total of 89.61% (138/154) unknown HRV strains were sequenced, and 79.22% (122/138) were analyzed. We identified 74 isolates (60.7%) of the HRV A species, 21 (17.2%) of the HRV B species and 27 isolates (22.1%) of the HRV C species. HRV species A and B caused ILI among adult patients, whereas HRV-C did not. The dynamics of infection among different species deserve further analysis.

Authors+Show Affiliations

Clinical Virology Laboratory, Infectious Diseases Unit, Medicine Department, Sao Paulo Federal University, Sao Paulo, Brazil. aripuana77@hotmail.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20981801

Citation

Watanabe, Aripuana, et al. "Rhinovirus Species and Their Clinical Presentation Among Different Risk Groups of Non-hospitalized Patients." Journal of Medical Virology, vol. 82, no. 12, 2010, pp. 2110-5.
Watanabe A, Carraro E, Kamikawa J, et al. Rhinovirus species and their clinical presentation among different risk groups of non-hospitalized patients. J Med Virol. 2010;82(12):2110-5.
Watanabe, A., Carraro, E., Kamikawa, J., Leal, E., Granato, C., & Bellei, N. (2010). Rhinovirus species and their clinical presentation among different risk groups of non-hospitalized patients. Journal of Medical Virology, 82(12), 2110-5. https://doi.org/10.1002/jmv.21914
Watanabe A, et al. Rhinovirus Species and Their Clinical Presentation Among Different Risk Groups of Non-hospitalized Patients. J Med Virol. 2010;82(12):2110-5. PubMed PMID: 20981801.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Rhinovirus species and their clinical presentation among different risk groups of non-hospitalized patients. AU - Watanabe,Aripuana, AU - Carraro,Emerson, AU - Kamikawa,Janete, AU - Leal,Elcio, AU - Granato,Celso, AU - Bellei,Nancy, PY - 2010/10/29/entrez PY - 2010/10/29/pubmed PY - 2011/2/24/medline SP - 2110 EP - 5 JF - Journal of medical virology JO - J Med Virol VL - 82 IS - 12 N2 - Infections caused by Human Rhinoviruses (HRVs) account for 25-50% of respiratory illnesses among individuals presenting influenza-like illness (ILI). HRVs could be classified in at least three species: HRV-A, HRV-B, and HRV-C. The HRV-C species has frequently been described among children and has led to severe illness resulting in hospitalization; however, the occurrence among adults is unknown. The aim of this study was to assess the clinical presentation and species distribution of HRV infections in different populations during 2001-2008. A total of 770 samples were collected. Subjects consisted of 136 adults from the general community and 207 health-care workers (2001-2003), 232 renal-transplanted outpatients (2002-2004), 70 children with congenital heart disease (2005) and 125 children from a day-care center (2008). Amplification of HRV genes was performed by reverse transcriptase-polymerase chain reaction (RT-PCR) and followed by sequencing and phylogenetic analysis. HRV was detected in 27.4% of samples (211/770), with 72 children (36.9%) and 139 adults infected (24.2%). A total of 89.61% (138/154) unknown HRV strains were sequenced, and 79.22% (122/138) were analyzed. We identified 74 isolates (60.7%) of the HRV A species, 21 (17.2%) of the HRV B species and 27 isolates (22.1%) of the HRV C species. HRV species A and B caused ILI among adult patients, whereas HRV-C did not. The dynamics of infection among different species deserve further analysis. SN - 1096-9071 UR - https://www.unboundmedicine.com/medline/citation/20981801/Rhinovirus_species_and_their_clinical_presentation_among_different_risk_groups_of_non_hospitalized_patients_ L2 - https://doi.org/10.1002/jmv.21914 DB - PRIME DP - Unbound Medicine ER -