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[Reproductive variables and risk of benign breast diseases. A case-control study].
Rev Saude Publica. 1990 Oct; 24(5):387-93.RS

Abstract

The purpose of the study was the identification of risk factors for benign breast diseases (BBD); 257 women with BBD diagnosed through pathological anatomy or cytology and a matched control for each were studied. Subjects were selected at The State University of Campinas Hospital and at a private clinic. To enter the study cases had to have a first diagnosis of BBD between October 1979 and August 1984. The following BBD were considered: dysplasia, fibroadenoma, cystic disease, papilloma and ductal ectasia. Reproductive variables were studied as risk factors, including menstrual ovulatory cycles. The date on which the BBD was diagnosed was defined as the index date. For controls, data were considered up to when they had reached the same age as the matched case on the occasion of her diagnosis. Nulliparity was a risk factor for BBD. First birth at or above age 30 was a protective factor. Women who had used contraceptive pills for two or more years had a significantly lower risk than those who had never used them. The number of menstrual ovulatory cycles was not found to be associated with the risk of BBD. The results obtained from the study of Brazilian women confirm some of the conclusions found in the literature, mainly those that associate some reproductive variables with the risk of BBD. A few of these variables are also confirmed as risk factors for breast cancer.

Authors+Show Affiliations

Departamento de Tocoginecologia, Faculdade de Ciências Médicas, Universidade Estadual de Campinas (UNICAMP), SP, Brasil.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

por

PubMed ID

2101530

Citation

Hardy, E E., et al. "[Reproductive Variables and Risk of Benign Breast Diseases. a Case-control Study]." Revista De Saude Publica, vol. 24, no. 5, 1990, pp. 387-93.
Hardy EE, Pinotti JA, Osis MJ, et al. [Reproductive variables and risk of benign breast diseases. A case-control study]. Rev Saude Publica. 1990;24(5):387-93.
Hardy, E. E., Pinotti, J. A., Osis, M. J., & Faúndes, A. (1990). [Reproductive variables and risk of benign breast diseases. A case-control study]. Revista De Saude Publica, 24(5), 387-93.
Hardy EE, et al. [Reproductive Variables and Risk of Benign Breast Diseases. a Case-control Study]. Rev Saude Publica. 1990;24(5):387-93. PubMed PMID: 2101530.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Reproductive variables and risk of benign breast diseases. A case-control study]. AU - Hardy,E E, AU - Pinotti,J A, AU - Osis,M J, AU - Faúndes,A, PY - 1990/10/1/pubmed PY - 1990/10/1/medline PY - 1990/10/1/entrez KW - Age Factors KW - Americas KW - Biology KW - Brazil KW - Case Control Studies KW - Contraception KW - Contraceptive Methods KW - Demographic Factors KW - Developing Countries KW - Family Planning KW - Fertility KW - Fertility Measurements KW - Latin America KW - Mammary Gland Effects KW - Menstrual Cycle KW - Menstruation KW - Nulliparity KW - Oral Contraceptives KW - Parity KW - Physiology KW - Population KW - Population Characteristics KW - Population Dynamics KW - Reproduction KW - Research Methodology KW - Risk Factors KW - South America KW - Studies SP - 387 EP - 93 JF - Revista de saude publica JO - Rev Saude Publica VL - 24 IS - 5 N2 - The purpose of the study was the identification of risk factors for benign breast diseases (BBD); 257 women with BBD diagnosed through pathological anatomy or cytology and a matched control for each were studied. Subjects were selected at The State University of Campinas Hospital and at a private clinic. To enter the study cases had to have a first diagnosis of BBD between October 1979 and August 1984. The following BBD were considered: dysplasia, fibroadenoma, cystic disease, papilloma and ductal ectasia. Reproductive variables were studied as risk factors, including menstrual ovulatory cycles. The date on which the BBD was diagnosed was defined as the index date. For controls, data were considered up to when they had reached the same age as the matched case on the occasion of her diagnosis. Nulliparity was a risk factor for BBD. First birth at or above age 30 was a protective factor. Women who had used contraceptive pills for two or more years had a significantly lower risk than those who had never used them. The number of menstrual ovulatory cycles was not found to be associated with the risk of BBD. The results obtained from the study of Brazilian women confirm some of the conclusions found in the literature, mainly those that associate some reproductive variables with the risk of BBD. A few of these variables are also confirmed as risk factors for breast cancer. SN - 0034-8910 UR - https://www.unboundmedicine.com/medline/citation/2101530/[Reproductive_variables_and_risk_of_benign_breast_diseases__A_case_control_study]_ L2 - https://medlineplus.gov/breastdiseases.html DB - PRIME DP - Unbound Medicine ER -