Tags

Type your tag names separated by a space and hit enter

Cheilitis glandularis: clinico-histopathological diagnostic criteria.
Oral Dis. 2011 Apr; 17(3):335-9.OD

Abstract

OBJECTIVES

To present a combination of clinical and histopathological criteria for diagnosing cheilitis glandularis (CG), and to evaluate the association between CG and squamous cell carcinoma (SCC).

MATERIALS AND METHODS

The medical literature in English was searched from 1950 to 2010 and selected demographic data, and clinical and histopathological features of CG were retrieved and analysed.

RESULTS

A total of 77 cases have been published and four new cases were added to the collective data. The clinical criteria applied included the coexistence of multiple lesions and mucoid/purulent discharge, while the histopathological criteria included two or more of the following findings: sialectasia, chronic inflammation, mucous/oncocytic metaplasia and mucin in ducts. Only 47 (58.0%) cases involving patients with a mean age of 48.5 ± 20.3 years and a male-to-female ratio of 2.9:1 fulfilled the criteria. The lower lip alone was most commonly affected (70.2%). CG was associated with SCC in only three cases (3.5%) for which there was a clear aetiological factor for the malignancy.

CONCLUSIONS

The proposed diagnostic criteria can assist in delineating true CG from a variety of lesions with a comparable clinical/histopathological presentation. CG in association with premalignant/malignant epithelial changes of the lower lip may represent secondary, reactive changes of the salivary glands.

Authors+Show Affiliations

Department of Oral Rehabilitation, The Maurice and Gabriela Goldschleger School of Dental Medicine, Tel Aviv University, Tel Aviv, Israel. shosh5@bezeqint.netNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

21029266

Citation

Reiter, S, et al. "Cheilitis Glandularis: Clinico-histopathological Diagnostic Criteria." Oral Diseases, vol. 17, no. 3, 2011, pp. 335-9.
Reiter S, Vered M, Yarom N, et al. Cheilitis glandularis: clinico-histopathological diagnostic criteria. Oral Dis. 2011;17(3):335-9.
Reiter, S., Vered, M., Yarom, N., Goldsmith, C., & Gorsky, M. (2011). Cheilitis glandularis: clinico-histopathological diagnostic criteria. Oral Diseases, 17(3), 335-9. https://doi.org/10.1111/j.1601-0825.2010.01762.x
Reiter S, et al. Cheilitis Glandularis: Clinico-histopathological Diagnostic Criteria. Oral Dis. 2011;17(3):335-9. PubMed PMID: 21029266.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cheilitis glandularis: clinico-histopathological diagnostic criteria. AU - Reiter,S, AU - Vered,M, AU - Yarom,N, AU - Goldsmith,C, AU - Gorsky,M, Y1 - 2010/10/28/ PY - 2010/10/30/entrez PY - 2010/10/30/pubmed PY - 2011/7/27/medline SP - 335 EP - 9 JF - Oral diseases JO - Oral Dis VL - 17 IS - 3 N2 - OBJECTIVES: To present a combination of clinical and histopathological criteria for diagnosing cheilitis glandularis (CG), and to evaluate the association between CG and squamous cell carcinoma (SCC). MATERIALS AND METHODS: The medical literature in English was searched from 1950 to 2010 and selected demographic data, and clinical and histopathological features of CG were retrieved and analysed. RESULTS: A total of 77 cases have been published and four new cases were added to the collective data. The clinical criteria applied included the coexistence of multiple lesions and mucoid/purulent discharge, while the histopathological criteria included two or more of the following findings: sialectasia, chronic inflammation, mucous/oncocytic metaplasia and mucin in ducts. Only 47 (58.0%) cases involving patients with a mean age of 48.5 ± 20.3 years and a male-to-female ratio of 2.9:1 fulfilled the criteria. The lower lip alone was most commonly affected (70.2%). CG was associated with SCC in only three cases (3.5%) for which there was a clear aetiological factor for the malignancy. CONCLUSIONS: The proposed diagnostic criteria can assist in delineating true CG from a variety of lesions with a comparable clinical/histopathological presentation. CG in association with premalignant/malignant epithelial changes of the lower lip may represent secondary, reactive changes of the salivary glands. SN - 1601-0825 UR - https://www.unboundmedicine.com/medline/citation/21029266/Cheilitis_glandularis:_clinico_histopathological_diagnostic_criteria_ L2 - https://doi.org/10.1111/j.1601-0825.2010.01762.x DB - PRIME DP - Unbound Medicine ER -