TY - JOUR T1 - Biologically active sesquiterpene coumarins from Ferula species. AU - Nazari,Zeinab Esmail, AU - Iranshahi,Mehrdad, Y1 - 2010/10/28/ PY - 2010/02/27/received PY - 2010/06/27/revised PY - 2010/09/07/accepted PY - 2010/10/30/entrez PY - 2010/10/30/pubmed PY - 2011/5/13/medline SP - 315 EP - 23 JF - Phytotherapy research : PTR JO - Phytother Res VL - 25 IS - 3 N2 - Extracts from different species of the genus Ferula (Apiaceae) have had various biomedical applications for many centuries. Many biological features of this genus such as cytotoxicity, antibacterial, antiviral, P-glycoprotein (P-gp) inhibitory and antiinflammatory activity have been attributed to sesquiterpene coumarins; structures containing a common coumarin group and a sesquiterpene moiety. This both highlights the importance of sesquiterpene coumarins as biologically active natural products and necessitates further studies on these compounds. Taking into account the versatile biological properties of compounds isolated from Ferula and the unprecedented interest in the application of natural products as a new generation of therapeutics, the present review will discuss reports on biological activities of sesquiterpene coumarins of the genus Ferula, from 1990 onwards. SN - 1099-1573 UR - https://www.unboundmedicine.com/medline/citation/21031633/Biologically_active_sesquiterpene_coumarins_from_Ferula_species_ L2 - https://doi.org/10.1002/ptr.3311 DB - PRIME DP - Unbound Medicine ER -