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Composition of a volatile extract of Eryngium duriaei subsp. juresianum (M. Laínz) M. Laínz, signalised by the antifungal activity.
J Pharm Biomed Anal. 2011 Feb 20; 54(3):619-22.JP

Abstract

The composition of a volatile extract of Eryngium duriaei subsp. juresianum, signalised by the antifungal activity (MIC values=0.16-0.32 μL mL(-1)) against several dermatophyte species (Trichophyton mentagrophytes, T. rubrum, Epidermophyton floccosum; T. verrucosum, T. mentagrophytes var interdigitale, Microsporum canis and M. gypseum) was established following a combined methodology of GC, GC-MS and an exclusive (13)C NMR technique that does not require prior isolation of compounds. Twenty-five components were identified accounting 84.6% of the whole composition. Major compound was found to be α-neocallitropsene (26.0%) although the dominance of caryophyllane derived compounds, the most probable responsible for the antifungal activity, namely isocaryophyllen-14-al (16.2%), 14-hidroxy-β-caryophyllene (13.4%), caryophyllene oxide (7.6%) and E-β-caryophyllene (6.3%).

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Authors+Show Affiliations

Cavaleiro C
Centro de Estudos Farmacêuticos/Faculdade de Farmácia, Universidade de Coimbra, 3000-548 Coimbra, Portugal. cavaleir@ff.uc.pt
Gonçalves MJ
No affiliation info available
Serra D
No affiliation info available
Santoro G
No affiliation info available
Tomi F
No affiliation info available
Bighelli A
No affiliation info available
Salgueiro L
No affiliation info available
Casanova J
No affiliation info available

MeSH

Antifungal AgentsArthrodermataceaeDermatomycosesEpidermophytonEryngiumHumansMicrobial Sensitivity TestsMicrosporumPlant Components, AerialPlant ExtractsPolycyclic SesquiterpenesSesquiterpenesTrichophyton

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21036502

Citation

Cavaleiro, Carlos, et al. "Composition of a Volatile Extract of Eryngium Duriaei Subsp. Juresianum (M. Laínz) M. Laínz, Signalised By the Antifungal Activity." Journal of Pharmaceutical and Biomedical Analysis, vol. 54, no. 3, 2011, pp. 619-22.
Cavaleiro C, Gonçalves MJ, Serra D, et al. Composition of a volatile extract of Eryngium duriaei subsp. juresianum (M. Laínz) M. Laínz, signalised by the antifungal activity. J Pharm Biomed Anal. 2011;54(3):619-22.
Cavaleiro, C., Gonçalves, M. J., Serra, D., Santoro, G., Tomi, F., Bighelli, A., Salgueiro, L., & Casanova, J. (2011). Composition of a volatile extract of Eryngium duriaei subsp. juresianum (M. Laínz) M. Laínz, signalised by the antifungal activity. Journal of Pharmaceutical and Biomedical Analysis, 54(3), 619-22. https://doi.org/10.1016/j.jpba.2010.09.039
Cavaleiro C, et al. Composition of a Volatile Extract of Eryngium Duriaei Subsp. Juresianum (M. Laínz) M. Laínz, Signalised By the Antifungal Activity. J Pharm Biomed Anal. 2011 Feb 20;54(3):619-22. PubMed PMID: 21036502.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Composition of a volatile extract of Eryngium duriaei subsp. juresianum (M. Laínz) M. Laínz, signalised by the antifungal activity. AU - Cavaleiro,Carlos, AU - Gonçalves,Maria José, AU - Serra,Diana, AU - Santoro,Giani, AU - Tomi,Felix, AU - Bighelli,Ange, AU - Salgueiro,Ligia, AU - Casanova,Joseph, Y1 - 2010/10/08/ PY - 2010/07/16/received PY - 2010/09/15/revised PY - 2010/09/30/accepted PY - 2010/11/2/entrez PY - 2010/11/3/pubmed PY - 2011/5/21/medline SP - 619 EP - 22 JF - Journal of pharmaceutical and biomedical analysis JO - J Pharm Biomed Anal VL - 54 IS - 3 N2 - The composition of a volatile extract of Eryngium duriaei subsp. juresianum, signalised by the antifungal activity (MIC values=0.16-0.32 μL mL(-1)) against several dermatophyte species (Trichophyton mentagrophytes, T. rubrum, Epidermophyton floccosum; T. verrucosum, T. mentagrophytes var interdigitale, Microsporum canis and M. gypseum) was established following a combined methodology of GC, GC-MS and an exclusive (13)C NMR technique that does not require prior isolation of compounds. Twenty-five components were identified accounting 84.6% of the whole composition. Major compound was found to be α-neocallitropsene (26.0%) although the dominance of caryophyllane derived compounds, the most probable responsible for the antifungal activity, namely isocaryophyllen-14-al (16.2%), 14-hidroxy-β-caryophyllene (13.4%), caryophyllene oxide (7.6%) and E-β-caryophyllene (6.3%). SN - 1873-264X UR - https://www.unboundmedicine.com/medline/citation/21036502/Composition_of_a_volatile_extract_of_Eryngium_duriaei_subsp__juresianum__M__Laínz__M__Laínz_signalised_by_the_antifungal_activity_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0731-7085(10)00573-X DB - PRIME DP - Unbound Medicine ER -