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Antiphospholipid syndrome: long-time research on pathogenic mechanisms has finally lead to new therapeutic strategies.
Expert Opin Ther Targets. 2010 Dec; 14(12):1279-82.EO

Abstract

The antiphospholipid syndrome is characterized by the presence of arterial or venous thrombosis or recurrent miscarriages in a patient with positive laboratory tests for antiphospholipid antibodies (anticardiolipin antibodies and/or lupus anticoagulant and/or anti-beta2-glycoprotein I). Despite the strong association between antiphospholipid antibodies and thrombosis and obstetric morbidity, their pathogenic role in the development of these clinical features has not been fully elucidated. However, the knowledge of new pathogenic mechanisms might identify novel therapeutic targets and therefore may improve the management of these patients.

Authors

No affiliation info availableNo affiliation info available

Pub Type(s)

Editorial

Language

eng

PubMed ID

21058919

Citation

Cervera, Ricard, and Gerard Espinosa. "Antiphospholipid Syndrome: Long-time Research On Pathogenic Mechanisms Has Finally Lead to New Therapeutic Strategies." Expert Opinion On Therapeutic Targets, vol. 14, no. 12, 2010, pp. 1279-82.
Cervera R, Espinosa G. Antiphospholipid syndrome: long-time research on pathogenic mechanisms has finally lead to new therapeutic strategies. Expert Opin Ther Targets. 2010;14(12):1279-82.
Cervera, R., & Espinosa, G. (2010). Antiphospholipid syndrome: long-time research on pathogenic mechanisms has finally lead to new therapeutic strategies. Expert Opinion On Therapeutic Targets, 14(12), 1279-82. https://doi.org/10.1517/14728222.2010.530900
Cervera R, Espinosa G. Antiphospholipid Syndrome: Long-time Research On Pathogenic Mechanisms Has Finally Lead to New Therapeutic Strategies. Expert Opin Ther Targets. 2010;14(12):1279-82. PubMed PMID: 21058919.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antiphospholipid syndrome: long-time research on pathogenic mechanisms has finally lead to new therapeutic strategies. AU - Cervera,Ricard, AU - Espinosa,Gerard, PY - 2010/11/10/entrez PY - 2010/11/10/pubmed PY - 2011/5/11/medline SP - 1279 EP - 82 JF - Expert opinion on therapeutic targets JO - Expert Opin Ther Targets VL - 14 IS - 12 N2 - The antiphospholipid syndrome is characterized by the presence of arterial or venous thrombosis or recurrent miscarriages in a patient with positive laboratory tests for antiphospholipid antibodies (anticardiolipin antibodies and/or lupus anticoagulant and/or anti-beta2-glycoprotein I). Despite the strong association between antiphospholipid antibodies and thrombosis and obstetric morbidity, their pathogenic role in the development of these clinical features has not been fully elucidated. However, the knowledge of new pathogenic mechanisms might identify novel therapeutic targets and therefore may improve the management of these patients. SN - 1744-7631 UR - https://www.unboundmedicine.com/medline/citation/21058919/Antiphospholipid_syndrome:_long_time_research_on_pathogenic_mechanisms_has_finally_lead_to_new_therapeutic_strategies_ L2 - https://www.tandfonline.com/doi/full/10.1517/14728222.2010.530900 DB - PRIME DP - Unbound Medicine ER -