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Clinical and serologic follow-up of four children and five adults with bird-fancier's lung.
J Allergy Clin Immunol. 1990 Mar; 85(3):655-60.JA

Abstract

We report the clinical and serologic findings in four children and five adults with chronic avian hypersensitivity pneumonitis. All subjects were treated with corticosteroids and bird exposure was reduced or eliminated. After a variable period, ranging from 6 months to 10 years, their clinical and serologic findings were reassessed. In terms of symptomatology, chest findings, and pulmonary functions, all four children improved and four adults improved, whereas one adult had a progressive clinical deterioration, ultimately resulting in her death 5 years later. In terms of serologic data, precipitating antibody tended to persist, and antibody to avian antigens, as determined by ELISA, remained positive, although the titer declined. We conclude that, while serologic positivity remains, the prognosis for children and adults with chronic avian hypersensitivity pneumonitis is very good, provided that irreversible damage has not already occurred at the time of diagnosis.

Authors+Show Affiliations

Department of Medicine, Northwestern University Medical School, Chicago, Ill. 60611.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

2107243

Citation

Grammer, L C., et al. "Clinical and Serologic Follow-up of Four Children and Five Adults With Bird-fancier's Lung." The Journal of Allergy and Clinical Immunology, vol. 85, no. 3, 1990, pp. 655-60.
Grammer LC, Roberts M, Lerner C, et al. Clinical and serologic follow-up of four children and five adults with bird-fancier's lung. J Allergy Clin Immunol. 1990;85(3):655-60.
Grammer, L. C., Roberts, M., Lerner, C., & Patterson, R. (1990). Clinical and serologic follow-up of four children and five adults with bird-fancier's lung. The Journal of Allergy and Clinical Immunology, 85(3), 655-60.
Grammer LC, et al. Clinical and Serologic Follow-up of Four Children and Five Adults With Bird-fancier's Lung. J Allergy Clin Immunol. 1990;85(3):655-60. PubMed PMID: 2107243.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinical and serologic follow-up of four children and five adults with bird-fancier's lung. AU - Grammer,L C, AU - Roberts,M, AU - Lerner,C, AU - Patterson,R, PY - 1990/3/1/pubmed PY - 1990/3/1/medline PY - 1990/3/1/entrez SP - 655 EP - 60 JF - The Journal of allergy and clinical immunology JO - J Allergy Clin Immunol VL - 85 IS - 3 N2 - We report the clinical and serologic findings in four children and five adults with chronic avian hypersensitivity pneumonitis. All subjects were treated with corticosteroids and bird exposure was reduced or eliminated. After a variable period, ranging from 6 months to 10 years, their clinical and serologic findings were reassessed. In terms of symptomatology, chest findings, and pulmonary functions, all four children improved and four adults improved, whereas one adult had a progressive clinical deterioration, ultimately resulting in her death 5 years later. In terms of serologic data, precipitating antibody tended to persist, and antibody to avian antigens, as determined by ELISA, remained positive, although the titer declined. We conclude that, while serologic positivity remains, the prognosis for children and adults with chronic avian hypersensitivity pneumonitis is very good, provided that irreversible damage has not already occurred at the time of diagnosis. SN - 0091-6749 UR - https://www.unboundmedicine.com/medline/citation/2107243/Clinical_and_serologic_follow_up_of_four_children_and_five_adults_with_bird_fancier's_lung_ L2 - https://linkinghub.elsevier.com/retrieve/pii/0091-6749(90)90107-F DB - PRIME DP - Unbound Medicine ER -