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Anticholinesterase activity of standardized extract of Illicium verum Hook. f. fruits.
Fitoterapia. 2011 Apr; 82(3):342-6.F

Abstract

Illicium verum is a well known spice in traditional Indian system for its therapeutic potential. The present study was aimed to evaluate the acetylcholinesterase (AChE) and butyrylcholinesterase inhibitory (BChE) activity of standardized extracts of I. verum and its oil. Present study confirmed that anethole contributed to the anticholinesterase activity of I. verum, with more specificity towards AChE. IC(50) for AChE and BChE inhibitory activity of anethole was 39.89±0.32 μg/mL and 75.35±1.47 μg/mL, whereas for the oil, 36.00±0.44 μg/mL and 70.65±0.96 μg/mL respectively. Therefore I. verum can be a good lead as anti-cholinesterase agent from natural resources.

Authors+Show Affiliations

School of Natural Product Studies, Department of Pharmaceutical Technology, Jadavpur University, Kolkata, India.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21075180

Citation

Bhadra, Santanu, et al. "Anticholinesterase Activity of Standardized Extract of Illicium Verum Hook. F. Fruits." Fitoterapia, vol. 82, no. 3, 2011, pp. 342-6.
Bhadra S, Mukherjee PK, Kumar NS, et al. Anticholinesterase activity of standardized extract of Illicium verum Hook. f. fruits. Fitoterapia. 2011;82(3):342-6.
Bhadra, S., Mukherjee, P. K., Kumar, N. S., & Bandyopadhyay, A. (2011). Anticholinesterase activity of standardized extract of Illicium verum Hook. f. fruits. Fitoterapia, 82(3), 342-6. https://doi.org/10.1016/j.fitote.2010.11.003
Bhadra S, et al. Anticholinesterase Activity of Standardized Extract of Illicium Verum Hook. F. Fruits. Fitoterapia. 2011;82(3):342-6. PubMed PMID: 21075180.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Anticholinesterase activity of standardized extract of Illicium verum Hook. f. fruits. AU - Bhadra,Santanu, AU - Mukherjee,Pulok K, AU - Kumar,N Satheesh, AU - Bandyopadhyay,A, Y1 - 2010/11/12/ PY - 2010/08/24/received PY - 2010/10/31/revised PY - 2010/11/02/accepted PY - 2010/11/16/entrez PY - 2010/11/16/pubmed PY - 2011/9/7/medline SP - 342 EP - 6 JF - Fitoterapia JO - Fitoterapia VL - 82 IS - 3 N2 - Illicium verum is a well known spice in traditional Indian system for its therapeutic potential. The present study was aimed to evaluate the acetylcholinesterase (AChE) and butyrylcholinesterase inhibitory (BChE) activity of standardized extracts of I. verum and its oil. Present study confirmed that anethole contributed to the anticholinesterase activity of I. verum, with more specificity towards AChE. IC(50) for AChE and BChE inhibitory activity of anethole was 39.89±0.32 μg/mL and 75.35±1.47 μg/mL, whereas for the oil, 36.00±0.44 μg/mL and 70.65±0.96 μg/mL respectively. Therefore I. verum can be a good lead as anti-cholinesterase agent from natural resources. SN - 1873-6971 UR - https://www.unboundmedicine.com/medline/citation/21075180/Anticholinesterase_activity_of_standardized_extract_of_Illicium_verum_Hook__f__fruits_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0367-326X(10)00283-2 DB - PRIME DP - Unbound Medicine ER -