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Treatment of alopecia areata with 308-nm excimer lamp.
J Dermatol. 2010 Dec; 37(12):1032-5.JD

Abstract

Alopecia areata is considered to be a T-cell mediated autoimmune disorder. The 308-nm excimer lamp is thought to be capable of inducing T-cell apoptosis in vitro, suggesting that the lamp might be effective for the treatment of alopecia areata. We examined the effectiveness of the 308-nm excimer lamp for the treatment of alopecia areata. We recruited three patients with single alopecia areata lesions that were resistant to conventional treatment. The lesions were exposed to a 308-nm excimer lamp at 2-weekly intervals. Hair regrowth was observed in all three patients after approximately 10 treatment sessions. Our study showed that exposure to the 308-nm excimer lamp effectively induced hair regrowth in solitary alopecia areata lesions. Apart from erythema, there were no significant adverse effects. Therefore, we suggest that it may be considered as a treatment modality for recalcitrant alopecia areata.

Authors+Show Affiliations

Department of Dermatology, Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan.No affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Evaluation Study
Journal Article

Language

eng

PubMed ID

21083705

Citation

Ohtsuki, Akiko, et al. "Treatment of Alopecia Areata With 308-nm Excimer Lamp." The Journal of Dermatology, vol. 37, no. 12, 2010, pp. 1032-5.
Ohtsuki A, Hasegawa T, Ikeda S. Treatment of alopecia areata with 308-nm excimer lamp. J Dermatol. 2010;37(12):1032-5.
Ohtsuki, A., Hasegawa, T., & Ikeda, S. (2010). Treatment of alopecia areata with 308-nm excimer lamp. The Journal of Dermatology, 37(12), 1032-5. https://doi.org/10.1111/j.1346-8138.2010.00942.x
Ohtsuki A, Hasegawa T, Ikeda S. Treatment of Alopecia Areata With 308-nm Excimer Lamp. J Dermatol. 2010;37(12):1032-5. PubMed PMID: 21083705.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Treatment of alopecia areata with 308-nm excimer lamp. AU - Ohtsuki,Akiko, AU - Hasegawa,Toshio, AU - Ikeda,Shigaku, Y1 - 2010/09/29/ PY - 2010/11/19/entrez PY - 2010/11/19/pubmed PY - 2011/3/18/medline SP - 1032 EP - 5 JF - The Journal of dermatology JO - J. Dermatol. VL - 37 IS - 12 N2 - Alopecia areata is considered to be a T-cell mediated autoimmune disorder. The 308-nm excimer lamp is thought to be capable of inducing T-cell apoptosis in vitro, suggesting that the lamp might be effective for the treatment of alopecia areata. We examined the effectiveness of the 308-nm excimer lamp for the treatment of alopecia areata. We recruited three patients with single alopecia areata lesions that were resistant to conventional treatment. The lesions were exposed to a 308-nm excimer lamp at 2-weekly intervals. Hair regrowth was observed in all three patients after approximately 10 treatment sessions. Our study showed that exposure to the 308-nm excimer lamp effectively induced hair regrowth in solitary alopecia areata lesions. Apart from erythema, there were no significant adverse effects. Therefore, we suggest that it may be considered as a treatment modality for recalcitrant alopecia areata. SN - 1346-8138 UR - https://www.unboundmedicine.com/medline/citation/21083705/Treatment_of_alopecia_areata_with_308_nm_excimer_lamp_ L2 - https://doi.org/10.1111/j.1346-8138.2010.00942.x DB - PRIME DP - Unbound Medicine ER -