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Minimal erythema dose and minimal melanogenesis dose relate better to objectively measured skin type than to Fitzpatricks skin type.
Photodermatol Photoimmunol Photomed. 2010 Dec; 26(6):280-4.PP

Abstract

BACKGROUND

Fitzpatrick skin type (FST I-IV) is a subjective expression of ultraviolet (UV) sensitivity based on erythema and tanning reactivity after a single exposure. Pigment protection factor (PPF) is an objective measurement of skin sensitivity in all skin types after a single exposure.

METHODS

The aim was to compare FST and PPF with clinically determined minimal erythema dose (MED) and minimal melanogenesis dose (MMD) in 84 persons with skin types I-V both after single and multiple exposures (one, four, five, six, or 12) to buttock and back skin.

RESULTS

FST was better correlated to MED than to MMD, and FST correlated better to constitutive than to facultative pigmented areas after multiple exposures rather than to a single exposure. PPF was generally much better correlated to MED and MMD than FST especially after a single exposure and multiple exposures with steady-state pigmentation. Multiple regression analyses showed that MED was the only significant, or most important determinator, of both FST and PPF. The correlation coefficient was highly significant for PPF (r² =82).

CONCLUSIONS

PPF is a better predictor of the individual UV sensitivity (linear relation) than FST (only 4 grades) and PPF can substitute FST.

Authors+Show Affiliations

Department of Dermatology, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark. hwul0001@bbh.regionh.dkNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21091784

Citation

Wulf, Hans Christian, et al. "Minimal Erythema Dose and Minimal Melanogenesis Dose Relate Better to Objectively Measured Skin Type Than to Fitzpatricks Skin Type." Photodermatology, Photoimmunology & Photomedicine, vol. 26, no. 6, 2010, pp. 280-4.
Wulf HC, Philipsen PA, Ravnbak MH. Minimal erythema dose and minimal melanogenesis dose relate better to objectively measured skin type than to Fitzpatricks skin type. Photodermatol Photoimmunol Photomed. 2010;26(6):280-4.
Wulf, H. C., Philipsen, P. A., & Ravnbak, M. H. (2010). Minimal erythema dose and minimal melanogenesis dose relate better to objectively measured skin type than to Fitzpatricks skin type. Photodermatology, Photoimmunology & Photomedicine, 26(6), 280-4. https://doi.org/10.1111/j.1600-0781.2010.00544.x
Wulf HC, Philipsen PA, Ravnbak MH. Minimal Erythema Dose and Minimal Melanogenesis Dose Relate Better to Objectively Measured Skin Type Than to Fitzpatricks Skin Type. Photodermatol Photoimmunol Photomed. 2010;26(6):280-4. PubMed PMID: 21091784.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Minimal erythema dose and minimal melanogenesis dose relate better to objectively measured skin type than to Fitzpatricks skin type. AU - Wulf,Hans Christian, AU - Philipsen,Peter A, AU - Ravnbak,Mette H, PY - 2010/11/25/entrez PY - 2010/11/26/pubmed PY - 2011/3/10/medline SP - 280 EP - 4 JF - Photodermatology, photoimmunology & photomedicine JO - Photodermatol Photoimmunol Photomed VL - 26 IS - 6 N2 - BACKGROUND: Fitzpatrick skin type (FST I-IV) is a subjective expression of ultraviolet (UV) sensitivity based on erythema and tanning reactivity after a single exposure. Pigment protection factor (PPF) is an objective measurement of skin sensitivity in all skin types after a single exposure. METHODS: The aim was to compare FST and PPF with clinically determined minimal erythema dose (MED) and minimal melanogenesis dose (MMD) in 84 persons with skin types I-V both after single and multiple exposures (one, four, five, six, or 12) to buttock and back skin. RESULTS: FST was better correlated to MED than to MMD, and FST correlated better to constitutive than to facultative pigmented areas after multiple exposures rather than to a single exposure. PPF was generally much better correlated to MED and MMD than FST especially after a single exposure and multiple exposures with steady-state pigmentation. Multiple regression analyses showed that MED was the only significant, or most important determinator, of both FST and PPF. The correlation coefficient was highly significant for PPF (r² =82). CONCLUSIONS: PPF is a better predictor of the individual UV sensitivity (linear relation) than FST (only 4 grades) and PPF can substitute FST. SN - 1600-0781 UR - https://www.unboundmedicine.com/medline/citation/21091784/Minimal_erythema_dose_and_minimal_melanogenesis_dose_relate_better_to_objectively_measured_skin_type_than_to_Fitzpatricks_skin_type_ L2 - https://doi.org/10.1111/j.1600-0781.2010.00544.x DB - PRIME DP - Unbound Medicine ER -