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[An antimicrobial resistance surveillance of gram-positive cocci isolated from 12 teaching hospitals in China in 2009].
Zhonghua Nei Ke Za Zhi. 2010 Sep; 49(9):735-40.ZN

Abstract

OBJECTIVE

To investigate antimicrobial resistance among gram-positive cocci in China in 2009.

METHODS

From June to December 2009, 1169 consecutive and non-repetitive gram-positive cocci were collected from 12 teaching hospitals at 9 cities. The minimal inhibitory concentration (MIC) of antibacterial agents was determined by agar dilution method.

RESULTS

The prevalences of methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant coagulase-negative Staphylococci (MRCoNS) were 45.3% (211/466) and 89.5% (214/239), respectively. The isolation rate of MRSA was 33.3% - 68.1% from different samples. All Staphylococci isolates were susceptible to vancomycin, teicoplanin and linezolid. Five point five percent (7/128) E.faecium strains were resistant to vancomycin. All E. faecalis strains were susceptible to vancomycin. About 99.1% (108/109) of E.faecalis and E.faecium were susceptible to linezolid. The prevalence of penicillin-intermediate Streptococcus pneumoniae (PISP) was 21.6% (48/222). Only 1 (0.5%, 1/222) Streptococcus pneumoniae strain was resistant to penicillin. Teicoplanin, vancomycin, linezolid and tigecycline were the most active agents against Streptococcus pneumoniae (susceptible rate 100%).

CONCLUSIONS

The high prevalence of methicillin-resistance is among Staphylococcus strains. Different samples show a different MRSA prevalence. Teicoplanin, vancomycin and linezolid show very high activity to Staphylococci, E. faecalis, E. faecium and Streptococcus pneumoniae.

Authors+Show Affiliations

Department of Clinical Laboratory, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

chi

PubMed ID

21092441

Citation

Sun, Hong-li, et al. "[An Antimicrobial Resistance Surveillance of Gram-positive Cocci Isolated From 12 Teaching Hospitals in China in 2009]." Zhonghua Nei Ke Za Zhi, vol. 49, no. 9, 2010, pp. 735-40.
Sun HL, Wang H, Chen MJ, et al. [An antimicrobial resistance surveillance of gram-positive cocci isolated from 12 teaching hospitals in China in 2009]. Zhonghua Nei Ke Za Zhi. 2010;49(9):735-40.
Sun, H. L., Wang, H., Chen, M. J., Liu, Y. M., Hu, Z. D., Liao, K., Chu, Y. Z., Lei, J. E., Zhang, B., Yu, Y. S., Hu, B. J., Sun, Z. Y., Zhang, Z., & He, Q. Y. (2010). [An antimicrobial resistance surveillance of gram-positive cocci isolated from 12 teaching hospitals in China in 2009]. Zhonghua Nei Ke Za Zhi, 49(9), 735-40.
Sun HL, et al. [An Antimicrobial Resistance Surveillance of Gram-positive Cocci Isolated From 12 Teaching Hospitals in China in 2009]. Zhonghua Nei Ke Za Zhi. 2010;49(9):735-40. PubMed PMID: 21092441.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [An antimicrobial resistance surveillance of gram-positive cocci isolated from 12 teaching hospitals in China in 2009]. AU - Sun,Hong-li, AU - Wang,Hui, AU - Chen,Min-jun, AU - Liu,Ying-mei, AU - Hu,Zhi-dong, AU - Liao,Kang, AU - Chu,Yun-zhuo, AU - Lei,Jin-e, AU - Zhang,Bing, AU - Yu,Yun-song, AU - Hu,Bi-jie, AU - Sun,Zi-yong, AU - Zhang,Zheng, AU - He,Qi-yong, PY - 2010/11/25/entrez PY - 2010/11/26/pubmed PY - 2011/12/13/medline SP - 735 EP - 40 JF - Zhonghua nei ke za zhi JO - Zhonghua Nei Ke Za Zhi VL - 49 IS - 9 N2 - OBJECTIVE: To investigate antimicrobial resistance among gram-positive cocci in China in 2009. METHODS: From June to December 2009, 1169 consecutive and non-repetitive gram-positive cocci were collected from 12 teaching hospitals at 9 cities. The minimal inhibitory concentration (MIC) of antibacterial agents was determined by agar dilution method. RESULTS: The prevalences of methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant coagulase-negative Staphylococci (MRCoNS) were 45.3% (211/466) and 89.5% (214/239), respectively. The isolation rate of MRSA was 33.3% - 68.1% from different samples. All Staphylococci isolates were susceptible to vancomycin, teicoplanin and linezolid. Five point five percent (7/128) E.faecium strains were resistant to vancomycin. All E. faecalis strains were susceptible to vancomycin. About 99.1% (108/109) of E.faecalis and E.faecium were susceptible to linezolid. The prevalence of penicillin-intermediate Streptococcus pneumoniae (PISP) was 21.6% (48/222). Only 1 (0.5%, 1/222) Streptococcus pneumoniae strain was resistant to penicillin. Teicoplanin, vancomycin, linezolid and tigecycline were the most active agents against Streptococcus pneumoniae (susceptible rate 100%). CONCLUSIONS: The high prevalence of methicillin-resistance is among Staphylococcus strains. Different samples show a different MRSA prevalence. Teicoplanin, vancomycin and linezolid show very high activity to Staphylococci, E. faecalis, E. faecium and Streptococcus pneumoniae. SN - 0578-1426 UR - https://www.unboundmedicine.com/medline/citation/21092441/[An_antimicrobial_resistance_surveillance_of_gram_positive_cocci_isolated_from_12_teaching_hospitals_in_China_in_2009]_ L2 - http://journal.yiigle.com/LinkIn.do?linkin_type=pubmed&issn=0578-1426&year=2010&vol=49&issue=9&fpage=735 DB - PRIME DP - Unbound Medicine ER -