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European guideline for the management of donovanosis, 2010.
Int J STD AIDS. 2010 Sep; 21(9):609-10.IJ

Abstract

Donovanosis is a rare sexually transmitted infection now mainly seen in sporadic cases in Papua New Guinea, South Africa, India, Brazil and Australia. The causative organism is Calymmatobacterium granulomatis though a proposal has been put forward that the organism be reclassified as Klebsiella granulomatis comb. nov. The incubation period is approximately 50 days with genital papules developing into ulcers that increase in size. Four types of lesions are described - ulcerogranulomatous, hypertrophic, necrotic and sclerotic. The diagnosis is usually confirmed by microscopic identification of characteristic Donovan bodies on stained tissue smears. More recently, polymerase chain reaction (PCR) methods have been developed. The recommended treatment is azithromycin 1 g weekly until complete healing is achieved.

Authors+Show Affiliations

Ealing Hospital, London, UK. nigel.o'farrell@eht.nhs.ukNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Practice Guideline

Language

eng

PubMed ID

21097731

Citation

O'Farrell, N, et al. "European Guideline for the Management of Donovanosis, 2010." International Journal of STD & AIDS, vol. 21, no. 9, 2010, pp. 609-10.
O'Farrell N, Moi H, IUSTI/WHO European STD guidelines Editorial Board. European guideline for the management of donovanosis, 2010. Int J STD AIDS. 2010;21(9):609-10.
O'Farrell, N., & Moi, H. (2010). European guideline for the management of donovanosis, 2010. International Journal of STD & AIDS, 21(9), 609-10. https://doi.org/10.1258/ijsa.2010.010245
O'Farrell N, Moi H, IUSTI/WHO European STD guidelines Editorial Board. European Guideline for the Management of Donovanosis, 2010. Int J STD AIDS. 2010;21(9):609-10. PubMed PMID: 21097731.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - European guideline for the management of donovanosis, 2010. AU - O'Farrell,N, AU - Moi,H, AU - ,, PY - 2010/11/25/entrez PY - 2010/11/26/pubmed PY - 2011/3/3/medline SP - 609 EP - 10 JF - International journal of STD & AIDS JO - Int J STD AIDS VL - 21 IS - 9 N2 - Donovanosis is a rare sexually transmitted infection now mainly seen in sporadic cases in Papua New Guinea, South Africa, India, Brazil and Australia. The causative organism is Calymmatobacterium granulomatis though a proposal has been put forward that the organism be reclassified as Klebsiella granulomatis comb. nov. The incubation period is approximately 50 days with genital papules developing into ulcers that increase in size. Four types of lesions are described - ulcerogranulomatous, hypertrophic, necrotic and sclerotic. The diagnosis is usually confirmed by microscopic identification of characteristic Donovan bodies on stained tissue smears. More recently, polymerase chain reaction (PCR) methods have been developed. The recommended treatment is azithromycin 1 g weekly until complete healing is achieved. SN - 1758-1052 UR - https://www.unboundmedicine.com/medline/citation/21097731/European_guideline_for_the_management_of_donovanosis,_2010. L2 - https://journals.sagepub.com/doi/10.1258/ijsa.2010.010245?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -