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Conservative management of screen-detected radial scars: role of mammotome excision.
J Clin Pathol. 2011 Jan; 64(1):65-8.JC

Abstract

AIMS

Traditionally, a core biopsy diagnosis of radial scar will prompt diagnostic surgery because of the risk of associated malignancy. However, in the absence of atypia, the risk of malignancy is low. The recent introduction of the mammotome device facilitates vacuum-assisted large-volume sampling of a lesion, such that a benign diagnosis may be accepted more confidently, and if the lesion has been entirely removed, it effectively becomes a therapeutic procedure. The aim of this study was to review the role of mammotome excision in the management of non-atypical radial scars in the screening population.

METHODS

Screen-detected radial scars diagnosed on core biopsy between July 2004 and September 2008 were identified from pathology records. From January 2006, the mammotome device was used to excise non-atypical radial scars on core biopsy, as an alternative to surgery.

RESULTS

22 core biopsy samples containing radial scars without atypia were included in the study; 14 were planned for mammotome excision and eight for diagnostic surgical excision. In the mammotome group, 78% (11/14) of patients had confirmation of non-atypical radial scars and thus avoided an operation. Three of the 14 cases planned for mammotome excision required surgery; in one case, the mammotome cores contained lobular in situ neoplasia, and, in two cases, attempts to sample the lesion with the mammotome were unsuccessful. Only one of the 22 cases ultimately proved malignant. This was a case of ductal carcinoma in situ arising within a radial scar, where the patient proceeded straight to surgery in view of discordance between radiological and pathological features.

CONCLUSION

Utilisation of mammotome excision in the management of non-atypical radial scars successfully avoided surgery in 78% of eligible patients. Pathologists have an important role in selecting patients for mammotome excision by excluding the presence of atypia.

Authors+Show Affiliations

Radiology Department, Leeds Teaching Hospitals NHS Trust, Leeds, UK.No affiliation info availableNo affiliation info available

Pub Type(s)

Evaluation Study
Journal Article

Language

eng

PubMed ID

21097791

Citation

Rajan, Sabrina, et al. "Conservative Management of Screen-detected Radial Scars: Role of Mammotome Excision." Journal of Clinical Pathology, vol. 64, no. 1, 2011, pp. 65-8.
Rajan S, Wason AM, Carder PJ. Conservative management of screen-detected radial scars: role of mammotome excision. J Clin Pathol. 2011;64(1):65-8.
Rajan, S., Wason, A. M., & Carder, P. J. (2011). Conservative management of screen-detected radial scars: role of mammotome excision. Journal of Clinical Pathology, 64(1), 65-8. https://doi.org/10.1136/jcp.2010.083485
Rajan S, Wason AM, Carder PJ. Conservative Management of Screen-detected Radial Scars: Role of Mammotome Excision. J Clin Pathol. 2011;64(1):65-8. PubMed PMID: 21097791.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Conservative management of screen-detected radial scars: role of mammotome excision. AU - Rajan,Sabrina, AU - Wason,Anne-Marie, AU - Carder,Pauline J, Y1 - 2010/11/20/ PY - 2010/11/25/entrez PY - 2010/11/26/pubmed PY - 2011/4/14/medline SP - 65 EP - 8 JF - Journal of clinical pathology JO - J Clin Pathol VL - 64 IS - 1 N2 - AIMS: Traditionally, a core biopsy diagnosis of radial scar will prompt diagnostic surgery because of the risk of associated malignancy. However, in the absence of atypia, the risk of malignancy is low. The recent introduction of the mammotome device facilitates vacuum-assisted large-volume sampling of a lesion, such that a benign diagnosis may be accepted more confidently, and if the lesion has been entirely removed, it effectively becomes a therapeutic procedure. The aim of this study was to review the role of mammotome excision in the management of non-atypical radial scars in the screening population. METHODS: Screen-detected radial scars diagnosed on core biopsy between July 2004 and September 2008 were identified from pathology records. From January 2006, the mammotome device was used to excise non-atypical radial scars on core biopsy, as an alternative to surgery. RESULTS: 22 core biopsy samples containing radial scars without atypia were included in the study; 14 were planned for mammotome excision and eight for diagnostic surgical excision. In the mammotome group, 78% (11/14) of patients had confirmation of non-atypical radial scars and thus avoided an operation. Three of the 14 cases planned for mammotome excision required surgery; in one case, the mammotome cores contained lobular in situ neoplasia, and, in two cases, attempts to sample the lesion with the mammotome were unsuccessful. Only one of the 22 cases ultimately proved malignant. This was a case of ductal carcinoma in situ arising within a radial scar, where the patient proceeded straight to surgery in view of discordance between radiological and pathological features. CONCLUSION: Utilisation of mammotome excision in the management of non-atypical radial scars successfully avoided surgery in 78% of eligible patients. Pathologists have an important role in selecting patients for mammotome excision by excluding the presence of atypia. SN - 1472-4146 UR - https://www.unboundmedicine.com/medline/citation/21097791/Conservative_management_of_screen_detected_radial_scars:_role_of_mammotome_excision_ L2 - https://jcp.bmj.com/lookup/pmidlookup?view=long&pmid=21097791 DB - PRIME DP - Unbound Medicine ER -