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Post infectious bronchiolitis obliterans in children.
Paediatr Respir Rev 2010; 11(4):233-9PR

Abstract

Bronchiolitis Obliterans (BO) is an infrequent chronic and obstructive lung disease secondary to an insult to the terminal airway and its surroundings. In children, the most common presentation is the post-infectious variant, closely related to a severe viral infection in the first three years of life. However, the increase in the number of lung and bone-marrow transplants has also been followed by an increase in post-transplant BO. Post-transplant BO is progressive while post-infectious BO does not seem to be, but both forms share some common pathways that result in a characteristic histopathology of bronchiolar obliteration. This review covers up-to-date evidence on epidemiology, diagnosis, treatment and prognosis of post-infectious bronchiolitis obliterans, including areas of controversy that need to be addressed in future studies.

Authors+Show Affiliations

Department of Paediatrics, Universidade Federal de Ciencias da Saude, Porto Alegre, Brazil. gbuenof@terra.com.brNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

21109182

Citation

Fischer, Gilberto B., et al. "Post Infectious Bronchiolitis Obliterans in Children." Paediatric Respiratory Reviews, vol. 11, no. 4, 2010, pp. 233-9.
Fischer GB, Sarria EE, Mattiello R, et al. Post infectious bronchiolitis obliterans in children. Paediatr Respir Rev. 2010;11(4):233-9.
Fischer, G. B., Sarria, E. E., Mattiello, R., Mocelin, H. T., & Castro-Rodriguez, J. A. (2010). Post infectious bronchiolitis obliterans in children. Paediatric Respiratory Reviews, 11(4), pp. 233-9. doi:10.1016/j.prrv.2010.07.005.
Fischer GB, et al. Post Infectious Bronchiolitis Obliterans in Children. Paediatr Respir Rev. 2010;11(4):233-9. PubMed PMID: 21109182.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Post infectious bronchiolitis obliterans in children. AU - Fischer,Gilberto B, AU - Sarria,Edgar E, AU - Mattiello,Rita, AU - Mocelin,Helena T, AU - Castro-Rodriguez,Jose A, Y1 - 2010/08/19/ PY - 2010/11/27/entrez PY - 2010/11/27/pubmed PY - 2011/4/6/medline SP - 233 EP - 9 JF - Paediatric respiratory reviews JO - Paediatr Respir Rev VL - 11 IS - 4 N2 - Bronchiolitis Obliterans (BO) is an infrequent chronic and obstructive lung disease secondary to an insult to the terminal airway and its surroundings. In children, the most common presentation is the post-infectious variant, closely related to a severe viral infection in the first three years of life. However, the increase in the number of lung and bone-marrow transplants has also been followed by an increase in post-transplant BO. Post-transplant BO is progressive while post-infectious BO does not seem to be, but both forms share some common pathways that result in a characteristic histopathology of bronchiolar obliteration. This review covers up-to-date evidence on epidemiology, diagnosis, treatment and prognosis of post-infectious bronchiolitis obliterans, including areas of controversy that need to be addressed in future studies. SN - 1526-0550 UR - https://www.unboundmedicine.com/medline/citation/21109182/Post_infectious_bronchiolitis_obliterans_in_children_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1526-0542(10)00064-3 DB - PRIME DP - Unbound Medicine ER -