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Risk factors for chronic post-traumatic stress disorder (PTSD) in SARS survivors.
Gen Hosp Psychiatry. 2010 Nov-Dec; 32(6):590-8.GH

Abstract

BACKGROUND

Post-traumatic stress disorder (PTSD) is one of the most prevalent long-term psychiatric diagnoses among survivors of severe acute respiratory syndrome (SARS).

OBJECTIVES

The objective of this study was to identify the predictors of chronic PTSD in SARS survivors.

DESIGN

PTSD at 30 months after the SARS outbreak was assessed by the Structured Clinical Interview for the DSM-IV. Survivors' demographic data, medical information and psychosocial variables were collected for risk factor analysis.

RESULTS

Multivariate logistic regression analysis showed that female gender as well as the presence of chronic medical illnesses diagnosed before the onset of SARS and avascular necrosis were independent predictors of PTSD at 30 months post-SARS. Associated factors included higher-chance external locus of control, higher functional disability and higher average pain intensity.

CONCLUSION

The study of PTSD at 30 months post-SARS showed that the predictive value of acute medical variables may fade out. Our findings do not support some prior hypotheses that the use of high dose corticosteroids is protective against the development of PTSD. On the contrary, the adversity both before and after the SARS outbreak may be more important in hindering recovery from PTSD. The risk factor analysis can not only improve the detection of hidden psychiatric complications but also provide insight for the possible model of care delivery for the SARS survivors. With the complex interaction of the biopsychosocial challenges of SARS, an integrated multidisciplinary clinic setting may be a superior approach in the long-term management of complicated PTSD cases.

Authors+Show Affiliations

Integrated Post-SARS Clinic, United Christian Hospital, Kwun Tong, Kowloon, Hong Kong. ucmakwc1@ha.org.hkNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

21112450

Citation

Mak, Ivan Wing Chit, et al. "Risk Factors for Chronic Post-traumatic Stress Disorder (PTSD) in SARS Survivors." General Hospital Psychiatry, vol. 32, no. 6, 2010, pp. 590-8.
Mak IW, Chu CM, Pan PC, et al. Risk factors for chronic post-traumatic stress disorder (PTSD) in SARS survivors. Gen Hosp Psychiatry. 2010;32(6):590-8.
Mak, I. W., Chu, C. M., Pan, P. C., Yiu, M. G., Ho, S. C., & Chan, V. L. (2010). Risk factors for chronic post-traumatic stress disorder (PTSD) in SARS survivors. General Hospital Psychiatry, 32(6), 590-8. https://doi.org/10.1016/j.genhosppsych.2010.07.007
Mak IW, et al. Risk Factors for Chronic Post-traumatic Stress Disorder (PTSD) in SARS Survivors. Gen Hosp Psychiatry. 2010 Nov-Dec;32(6):590-8. PubMed PMID: 21112450.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Risk factors for chronic post-traumatic stress disorder (PTSD) in SARS survivors. AU - Mak,Ivan Wing Chit, AU - Chu,Chung Ming, AU - Pan,Pey Chyou, AU - Yiu,Michael Gar Chung, AU - Ho,Suzanne C, AU - Chan,Veronica Lee, Y1 - 2010/09/15/ PY - 2010/01/11/received PY - 2010/07/19/revised PY - 2010/07/20/accepted PY - 2010/11/30/entrez PY - 2010/11/30/pubmed PY - 2011/4/5/medline SP - 590 EP - 8 JF - General hospital psychiatry JO - Gen Hosp Psychiatry VL - 32 IS - 6 N2 - BACKGROUND: Post-traumatic stress disorder (PTSD) is one of the most prevalent long-term psychiatric diagnoses among survivors of severe acute respiratory syndrome (SARS). OBJECTIVES: The objective of this study was to identify the predictors of chronic PTSD in SARS survivors. DESIGN: PTSD at 30 months after the SARS outbreak was assessed by the Structured Clinical Interview for the DSM-IV. Survivors' demographic data, medical information and psychosocial variables were collected for risk factor analysis. RESULTS: Multivariate logistic regression analysis showed that female gender as well as the presence of chronic medical illnesses diagnosed before the onset of SARS and avascular necrosis were independent predictors of PTSD at 30 months post-SARS. Associated factors included higher-chance external locus of control, higher functional disability and higher average pain intensity. CONCLUSION: The study of PTSD at 30 months post-SARS showed that the predictive value of acute medical variables may fade out. Our findings do not support some prior hypotheses that the use of high dose corticosteroids is protective against the development of PTSD. On the contrary, the adversity both before and after the SARS outbreak may be more important in hindering recovery from PTSD. The risk factor analysis can not only improve the detection of hidden psychiatric complications but also provide insight for the possible model of care delivery for the SARS survivors. With the complex interaction of the biopsychosocial challenges of SARS, an integrated multidisciplinary clinic setting may be a superior approach in the long-term management of complicated PTSD cases. SN - 1873-7714 UR - https://www.unboundmedicine.com/medline/citation/21112450/Risk_factors_for_chronic_post_traumatic_stress_disorder__PTSD__in_SARS_survivors_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0163-8343(10)00145-3 DB - PRIME DP - Unbound Medicine ER -