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Anticoagulation and antiplatelet effects of semax under conditions of acute and chronic immobilization stress.
Bull Exp Biol Med. 2010 Jul; 149(1):44-6.BE

Abstract

The effects of semax on anticoagulant, fibrinolytic, and platelet components of the anticoagulation system were studied on albino rats under conditions of acute and chronic immobilization stress. Semax exhibited a protective antistress effect after repeated intranasal administration under conditions of hypercoagulation developing in response to immobilization stress of different degree. The effect manifested in stimulation of the anticoagulation system.

Authors+Show Affiliations

Grigorjeva ME
Laboratory of Defense Systems of Blood, Department of Human and Animal Physiology, Biological Faculty, M. V. Lomonosov Moscow University, Russsia. mgrigorjeva@mail.ru
Lyapina LA
No affiliation info available

MeSH

Administration, IntranasalAdrenocorticotropic HormoneAnimalsBlood CoagulationBlood PlateletsFibrinolysisMalePeptide FragmentsRatsRestraint, PhysicalStress, Physiological

Pub Type(s)

Journal Article

Language

eng rus

PubMed ID

21113455

Citation

Grigorjeva, M E., and L A. Lyapina. "Anticoagulation and Antiplatelet Effects of Semax Under Conditions of Acute and Chronic Immobilization Stress." Bulletin of Experimental Biology and Medicine, vol. 149, no. 1, 2010, pp. 44-6.
Grigorjeva ME, Lyapina LA. Anticoagulation and antiplatelet effects of semax under conditions of acute and chronic immobilization stress. Bull Exp Biol Med. 2010;149(1):44-6.
Grigorjeva, M. E., & Lyapina, L. A. (2010). Anticoagulation and antiplatelet effects of semax under conditions of acute and chronic immobilization stress. Bulletin of Experimental Biology and Medicine, 149(1), 44-6.
Grigorjeva ME, Lyapina LA. Anticoagulation and Antiplatelet Effects of Semax Under Conditions of Acute and Chronic Immobilization Stress. Bull Exp Biol Med. 2010;149(1):44-6. PubMed PMID: 21113455.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Anticoagulation and antiplatelet effects of semax under conditions of acute and chronic immobilization stress. AU - Grigorjeva,M E, AU - Lyapina,L A, PY - 2010/11/30/entrez PY - 2010/11/30/pubmed PY - 2011/3/3/medline SP - 44 EP - 6 JF - Bulletin of experimental biology and medicine JO - Bull Exp Biol Med VL - 149 IS - 1 N2 - The effects of semax on anticoagulant, fibrinolytic, and platelet components of the anticoagulation system were studied on albino rats under conditions of acute and chronic immobilization stress. Semax exhibited a protective antistress effect after repeated intranasal administration under conditions of hypercoagulation developing in response to immobilization stress of different degree. The effect manifested in stimulation of the anticoagulation system. SN - 1573-8221 UR - https://www.unboundmedicine.com/medline/citation/21113455/Anticoagulation_and_antiplatelet_effects_of_semax_under_conditions_of_acute_and_chronic_immobilization_stress_ L2 - https://dx.doi.org/10.1007/s10517-010-0871-x DB - PRIME DP - Unbound Medicine ER -