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Nervous system Lyme disease.
J R Coll Physicians Edinb. 2010 Sep; 40(3):248-55.JR

Abstract

Lyme disease, the multi-system infection caused by the tick-borne spirochaete Borrelia burgdorferi, can involve the nervous system, most commonly causing, alone or in combination, lymphocytic meningitis or abnormalities of cranial or peripheral nerves, the latter most typically presenting as a painful radicular syndrome. Diagnosis is based on appropriately used, standard serological tests; in instances where the central nervous system is involved, cerebrospinal fluid assessment for organism-specific antibodies can be useful. Treatment with any of several standard regimens of oral or parenteral antimicrobials is highly effective. Prolonged treatment beyond four weeks is rarely if ever warranted, and carries significant risk.

Authors+Show Affiliations

Atlantic Neuroscience Institute, Summit, New Jersey, USA. john.halperin@atlantichealth.org

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

21127770

Citation

Halperin, J J.. "Nervous System Lyme Disease." The Journal of the Royal College of Physicians of Edinburgh, vol. 40, no. 3, 2010, pp. 248-55.
Halperin JJ. Nervous system Lyme disease. J R Coll Physicians Edinb. 2010;40(3):248-55.
Halperin, J. J. (2010). Nervous system Lyme disease. The Journal of the Royal College of Physicians of Edinburgh, 40(3), 248-55. https://doi.org/10.4997/JRCPE.2010.314
Halperin JJ. Nervous System Lyme Disease. J R Coll Physicians Edinb. 2010;40(3):248-55. PubMed PMID: 21127770.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Nervous system Lyme disease. A1 - Halperin,J J, PY - 2010/12/4/entrez PY - 2010/12/4/pubmed PY - 2011/1/21/medline SP - 248 EP - 55 JF - The journal of the Royal College of Physicians of Edinburgh JO - J R Coll Physicians Edinb VL - 40 IS - 3 N2 - Lyme disease, the multi-system infection caused by the tick-borne spirochaete Borrelia burgdorferi, can involve the nervous system, most commonly causing, alone or in combination, lymphocytic meningitis or abnormalities of cranial or peripheral nerves, the latter most typically presenting as a painful radicular syndrome. Diagnosis is based on appropriately used, standard serological tests; in instances where the central nervous system is involved, cerebrospinal fluid assessment for organism-specific antibodies can be useful. Treatment with any of several standard regimens of oral or parenteral antimicrobials is highly effective. Prolonged treatment beyond four weeks is rarely if ever warranted, and carries significant risk. SN - 1478-2715 UR - https://www.unboundmedicine.com/medline/citation/21127770/Nervous_system_Lyme_disease_ L2 - http://www.diseaseinfosearch.org/result/9677 DB - PRIME DP - Unbound Medicine ER -