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Specificity of posttraumatic stress disorder symptoms: an investigation of comorbidity between posttraumatic stress disorder symptoms and depression in treatment-seeking veterans.
J Nerv Ment Dis. 2010 Dec; 198(12):885-90.JN

Abstract

In response to high levels of comorbidity and symptom overlap between posttraumatic stress disorder (PTSD), major depressive disorder (MDD), and other disorders, much attention has been devoted to the role of specific and nonspecific symptoms among the disorders. The present study investigated the overlapping symptoms of PTSD and MDD in treatment-seeking veterans. Exploratory factor analyses were used to identify latent factors of both self-reported and clinician-rated symptoms of PTSD and MDD. Results of exploratory factor analyses supported a 2-factor model representing symptoms of depression and PTSD; however, a subset of PTSD symptoms, characterized by emotional numbing and dysphoria, loaded onto the depression factor, rather than the PTSD factor. These nonspecific PTSD symptoms were predictive of comorbid MDD and increased depression symptomatology in patients with PTSD. Together, these findings demonstrate the importance of accounting for nonspecific symptoms in diagnosis and treatment of PTSD, highlighting a need for revisions to our current diagnostics.

Authors+Show Affiliations

Ralph H. Johnson Veterans Administration Medical Center, Charleston, SC 29401, USA. grosd@musc.eduNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

21135640

Citation

Gros, Daniel F., et al. "Specificity of Posttraumatic Stress Disorder Symptoms: an Investigation of Comorbidity Between Posttraumatic Stress Disorder Symptoms and Depression in Treatment-seeking Veterans." The Journal of Nervous and Mental Disease, vol. 198, no. 12, 2010, pp. 885-90.
Gros DF, Simms LJ, Acierno R. Specificity of posttraumatic stress disorder symptoms: an investigation of comorbidity between posttraumatic stress disorder symptoms and depression in treatment-seeking veterans. J Nerv Ment Dis. 2010;198(12):885-90.
Gros, D. F., Simms, L. J., & Acierno, R. (2010). Specificity of posttraumatic stress disorder symptoms: an investigation of comorbidity between posttraumatic stress disorder symptoms and depression in treatment-seeking veterans. The Journal of Nervous and Mental Disease, 198(12), 885-90. https://doi.org/10.1097/NMD.0b013e3181fe7410
Gros DF, Simms LJ, Acierno R. Specificity of Posttraumatic Stress Disorder Symptoms: an Investigation of Comorbidity Between Posttraumatic Stress Disorder Symptoms and Depression in Treatment-seeking Veterans. J Nerv Ment Dis. 2010;198(12):885-90. PubMed PMID: 21135640.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Specificity of posttraumatic stress disorder symptoms: an investigation of comorbidity between posttraumatic stress disorder symptoms and depression in treatment-seeking veterans. AU - Gros,Daniel F, AU - Simms,Leonard J, AU - Acierno,Ron, PY - 2010/12/8/entrez PY - 2010/12/8/pubmed PY - 2011/1/8/medline SP - 885 EP - 90 JF - The Journal of nervous and mental disease JO - J Nerv Ment Dis VL - 198 IS - 12 N2 - In response to high levels of comorbidity and symptom overlap between posttraumatic stress disorder (PTSD), major depressive disorder (MDD), and other disorders, much attention has been devoted to the role of specific and nonspecific symptoms among the disorders. The present study investigated the overlapping symptoms of PTSD and MDD in treatment-seeking veterans. Exploratory factor analyses were used to identify latent factors of both self-reported and clinician-rated symptoms of PTSD and MDD. Results of exploratory factor analyses supported a 2-factor model representing symptoms of depression and PTSD; however, a subset of PTSD symptoms, characterized by emotional numbing and dysphoria, loaded onto the depression factor, rather than the PTSD factor. These nonspecific PTSD symptoms were predictive of comorbid MDD and increased depression symptomatology in patients with PTSD. Together, these findings demonstrate the importance of accounting for nonspecific symptoms in diagnosis and treatment of PTSD, highlighting a need for revisions to our current diagnostics. SN - 1539-736X UR - https://www.unboundmedicine.com/medline/citation/21135640/Specificity_of_posttraumatic_stress_disorder_symptoms:_an_investigation_of_comorbidity_between_posttraumatic_stress_disorder_symptoms_and_depression_in_treatment_seeking_veterans_ L2 - https://doi.org/10.1097/NMD.0b013e3181fe7410 DB - PRIME DP - Unbound Medicine ER -