Tags

Type your tag names separated by a space and hit enter

[Predictive value of clinical features and nocturnal oximetry for the detection of obstructive sleep apnea syndrome].
Rev Med Chil. 2010 Aug; 138(8):941-50.RM

Abstract

BACKGROUND

Obstructive sleep apnea syndrome (OSA) is an important cause of morbidity and mortality in adults.

AIM

To evaluate the diagnostic value of clinical features and oximetric data to screen for obstructive sleep apnea before performing polysomnograpy or respiratory polygraphy.

MATERIAL AND METHODS

We studied 328 consecutive adult patients referred for snoring or excessive daytime sleepiness to a sleep clinic in whom a standardized questionnaire and the Sleepiness Epworth Scale were performed and body mass index (BMI), cervical circumference (CC), and nocturnal oximetry were measured.

RESULTS

Fifty three percent (n = 173) had evidence of clinically significant OSA (apnea/hypopnea index (AHI) > 15 events/h). Patients with OSA were more likely to be male, obese (BMI ≥ 26 kg/m²), smokers, to have a thick neck (CC > 41 cm), and to have a significant greater prevalence of relative reported apneas and excessive daytime sleepiness, as determined by Epworth scale. Male gender (Odds ratio (OR): 4.00; 95% confidence intervals (CI): 1.59-10.0, p = 0.003), BMI ≥ 26 kg/m² (OR: 3.68; 95%CI: 1.59-8.49, p = 0.002), smoking (OR: 2.29; 95% CI: 1.17-4.47, p = 0.015), Epworth index > 13 (OR: 2.65; 95% CI: 1.35-5.23, p = 0.005) and duration of symptoms over 2 years (OR: 2.35; 95% CI: 1.20-4.58, p = 0.012) were significant independent predictors of OSA. In nocturnal oximetry, the lowest SpO2 (SpO2 min) and the length of registries below 90% (CT-90) were independent predictors of OSA and both correlated significantly with AHI (r = -0.49 and r = 0.46 respectively, p < 0.001).

CONCLUSIONS

No single factor was usefully predictive of obstructive sleep apnea. However, combining clinical features and oximetry data may be appropriate to detect clinically significant OSA patients.

Authors+Show Affiliations

Departamento de Enfermedades respiratorias, Pontifica Universidad de Chile, Santiago, Chile. fsaldias@med.puc.clNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

spa

PubMed ID

21140050

Citation

Saldías P, Fernando, et al. "[Predictive Value of Clinical Features and Nocturnal Oximetry for the Detection of Obstructive Sleep Apnea Syndrome]." Revista Medica De Chile, vol. 138, no. 8, 2010, pp. 941-50.
Saldías P F, Jorquera A J, Díaz P O. [Predictive value of clinical features and nocturnal oximetry for the detection of obstructive sleep apnea syndrome]. Rev Med Chil. 2010;138(8):941-50.
Saldías P, F., Jorquera A, J., & Díaz P, O. (2010). [Predictive value of clinical features and nocturnal oximetry for the detection of obstructive sleep apnea syndrome]. Revista Medica De Chile, 138(8), 941-50. https://doi.org//S0034-98872010000800001
Saldías P F, Jorquera A J, Díaz P O. [Predictive Value of Clinical Features and Nocturnal Oximetry for the Detection of Obstructive Sleep Apnea Syndrome]. Rev Med Chil. 2010;138(8):941-50. PubMed PMID: 21140050.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Predictive value of clinical features and nocturnal oximetry for the detection of obstructive sleep apnea syndrome]. AU - Saldías P,Fernando, AU - Jorquera A,Jorge, AU - Díaz P,Orlando, Y1 - 2010/11/26/ PY - 2010/12/9/entrez PY - 2010/12/9/pubmed PY - 2011/11/15/medline SP - 941 EP - 50 JF - Revista medica de Chile JO - Rev Med Chil VL - 138 IS - 8 N2 - BACKGROUND: Obstructive sleep apnea syndrome (OSA) is an important cause of morbidity and mortality in adults. AIM: To evaluate the diagnostic value of clinical features and oximetric data to screen for obstructive sleep apnea before performing polysomnograpy or respiratory polygraphy. MATERIAL AND METHODS: We studied 328 consecutive adult patients referred for snoring or excessive daytime sleepiness to a sleep clinic in whom a standardized questionnaire and the Sleepiness Epworth Scale were performed and body mass index (BMI), cervical circumference (CC), and nocturnal oximetry were measured. RESULTS: Fifty three percent (n = 173) had evidence of clinically significant OSA (apnea/hypopnea index (AHI) > 15 events/h). Patients with OSA were more likely to be male, obese (BMI ≥ 26 kg/m²), smokers, to have a thick neck (CC > 41 cm), and to have a significant greater prevalence of relative reported apneas and excessive daytime sleepiness, as determined by Epworth scale. Male gender (Odds ratio (OR): 4.00; 95% confidence intervals (CI): 1.59-10.0, p = 0.003), BMI ≥ 26 kg/m² (OR: 3.68; 95%CI: 1.59-8.49, p = 0.002), smoking (OR: 2.29; 95% CI: 1.17-4.47, p = 0.015), Epworth index > 13 (OR: 2.65; 95% CI: 1.35-5.23, p = 0.005) and duration of symptoms over 2 years (OR: 2.35; 95% CI: 1.20-4.58, p = 0.012) were significant independent predictors of OSA. In nocturnal oximetry, the lowest SpO2 (SpO2 min) and the length of registries below 90% (CT-90) were independent predictors of OSA and both correlated significantly with AHI (r = -0.49 and r = 0.46 respectively, p < 0.001). CONCLUSIONS: No single factor was usefully predictive of obstructive sleep apnea. However, combining clinical features and oximetry data may be appropriate to detect clinically significant OSA patients. SN - 0034-9887 UR - https://www.unboundmedicine.com/medline/citation/21140050/[Predictive_value_of_clinical_features_and_nocturnal_oximetry_for_the_detection_of_obstructive_sleep_apnea_syndrome]_ L2 - http://www.scielo.cl/scielo.php?script=sci_arttext&amp;pid=S0034-98872010000800001&amp;lng=en&amp;nrm=iso&amp;tlng=en DB - PRIME DP - Unbound Medicine ER -