Citation
Lee, Hye Won, et al. "Desmopressin Is an Effective Treatment for Mixed Nocturia With Nocturnal Polyuria and Decreased Nocturnal Bladder Capacity." Journal of Korean Medical Science, vol. 25, no. 12, 2010, pp. 1792-7.
Lee HW, Choo MS, Lee JG, et al. Desmopressin is an effective treatment for mixed nocturia with nocturnal polyuria and decreased nocturnal bladder capacity. J Korean Med Sci. 2010;25(12):1792-7.
Lee, H. W., Choo, M. S., Lee, J. G., Park, C. H., Paick, J. S., Lee, J. Z., Han, D. H., Park, W. H., & Lee, K. S. (2010). Desmopressin is an effective treatment for mixed nocturia with nocturnal polyuria and decreased nocturnal bladder capacity. Journal of Korean Medical Science, 25(12), 1792-7. https://doi.org/10.3346/jkms.2010.25.12.1792
Lee HW, et al. Desmopressin Is an Effective Treatment for Mixed Nocturia With Nocturnal Polyuria and Decreased Nocturnal Bladder Capacity. J Korean Med Sci. 2010;25(12):1792-7. PubMed PMID: 21165296.
TY - JOUR
T1 - Desmopressin is an effective treatment for mixed nocturia with nocturnal polyuria and decreased nocturnal bladder capacity.
AU - Lee,Hye Won,
AU - Choo,Myung-Soo,
AU - Lee,Jeong Gu,
AU - Park,Choal Hee,
AU - Paick,Jae-Seung,
AU - Lee,Jeong Zoo,
AU - Han,Deok Hyun,
AU - Park,Won Hee,
AU - Lee,Kyu-Sung,
Y1 - 2010/11/24/
PY - 2010/04/21/received
PY - 2010/07/22/accepted
PY - 2010/12/18/entrez
PY - 2010/12/18/pubmed
PY - 2011/4/8/medline
KW - Deamino Arginine Vasopressin
KW - Hyponatremia
KW - Nocturia
KW - Nocturnal Polyuria
KW - Urinary Bladder
SP - 1792
EP - 7
JF - Journal of Korean medical science
JO - J Korean Med Sci
VL - 25
IS - 12
N2 - To investigate the efficacy and safety of desmopressin in patients with mixed nocturia, Patients aged ≥ 18 yr with mixed nocturia (≥ 2 voids/night and a nocturnal polyuria index [NPi] >33% and a nocturnal bladder capacity index [NBCi] >1) were recruited. The optimum dose of oral desmopressin was determined during a 3-week dose-titration period and the determined dose was maintained for 4 weeks. The efficacy was assessed by the frequency-volume charts and the sleep questionnaire. The primary endpoint was the proportion of patients with a 50% or greater reduction in the number of nocturnal voids (NV) compared with baseline. Among 103 patients enrolled, 94 (79 men and 15 women) were included in the analysis. The proportion of patients with a 50% or greater reduction in NV was 68 (72%). The mean number of NV decreased significantly (3.20 to 1.34) and the mean nocturnal urine volume, nocturia index, NPi, and NBCi decreased significantly. The mean duration of sleep until the first NV was prolonged from 118.4 ± 44.1 to 220.3 ± 90.7 min (P<0.001). The overall impression of patients about their quality of sleep improved. Adverse events occurred in 6 patients, including one asymptomatic hyponatremia. Desmopressin is an effective and well-tolerated treatment for mixed nocturia.
SN - 1598-6357
UR - https://www.unboundmedicine.com/medline/citation/21165296/Desmopressin_is_an_effective_treatment_for_mixed_nocturia_with_nocturnal_polyuria_and_decreased_nocturnal_bladder_capacity_
L2 - https://jkms.org/DOIx.php?id=10.3346/jkms.2010.25.12.1792
DB - PRIME
DP - Unbound Medicine
ER -