Tags

Type your tag names separated by a space and hit enter

Haematolohical profile of subacute oral toxicity of molybdenum and ameliorative efficacy of copper salt in goats.
Toxicol Int. 2010 Jul; 17(2):82-5.TI

Abstract

Molybdenum toxicity produces a state of secondary hypocuprosis, resulting into alterations in normal hematological profile. In the present study, ammonium molybdate alone and with copper sulfate (II) pentahydrate (ameliorative agent) was administered orally for 30 consecutive days in healthy goats of group 1 and 2, respectively, to access the effect on the hematological profile on different predetermined days of dosing. Administration of ammonium molybdate alone produced significant decline in the mean values of hemoglobin (Hb), packed cell volume (PCV), total leukocyte count (TLC), total erythrocyte count (TEC), and mean corpuscular hemoglobin concentration (MCHC), with a significant increase in neutrophil level and mean corpuscular volume (MCV). However, values of erythrocyte sedimentation rate, mean corpuscular hemoglobin, and differential leukocyte count were not significantly altered. On comparing observations of ameliorative group with the group 1 goats, it is concluded that the ameliorative copper salt has beneficial effects in alleviating the alterations in the values of Hb, PCV, TLC, TEC, MCV, MCHC, and neutrophils.

Authors+Show Affiliations

Divisions of Pharmacology and Toxicology, Faculty of Veterinary Sciences and Animal Husbandry, SKUAST, R.S. Pura, Jammu, Jammu and Kashmir, India.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

21170251

Citation

Kusum, , et al. "Haematolohical Profile of Subacute Oral Toxicity of Molybdenum and Ameliorative Efficacy of Copper Salt in Goats." Toxicology International, vol. 17, no. 2, 2010, pp. 82-5.
Kusum , Raina R, Verma PK, et al. Haematolohical profile of subacute oral toxicity of molybdenum and ameliorative efficacy of copper salt in goats. Toxicology international. 2010;17(2):82-5.
Kusum, ., Raina, R., Verma, P. K., Pankaj, N. K., Kant, V., Kumar, J., & Srivastava, A. K. (2010). Haematolohical profile of subacute oral toxicity of molybdenum and ameliorative efficacy of copper salt in goats. Toxicology International, 17(2), 82-5. https://doi.org/10.4103/0971-6580.72676
Kusum , et al. Haematolohical Profile of Subacute Oral Toxicity of Molybdenum and Ameliorative Efficacy of Copper Salt in Goats. Toxicology international. 2010;17(2):82-5. PubMed PMID: 21170251.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Haematolohical profile of subacute oral toxicity of molybdenum and ameliorative efficacy of copper salt in goats. AU - Kusum,, AU - Raina,R, AU - Verma,P K, AU - Pankaj,N K, AU - Kant,V, AU - Kumar,J, AU - Srivastava,A K, PY - 2010/12/21/entrez PY - 2010/12/21/pubmed PY - 2010/12/21/medline KW - Ammonium molybdate KW - copper sulfate KW - goats KW - hematological profile SP - 82 EP - 5 JF - Toxicology international VL - 17 IS - 2 N2 - Molybdenum toxicity produces a state of secondary hypocuprosis, resulting into alterations in normal hematological profile. In the present study, ammonium molybdate alone and with copper sulfate (II) pentahydrate (ameliorative agent) was administered orally for 30 consecutive days in healthy goats of group 1 and 2, respectively, to access the effect on the hematological profile on different predetermined days of dosing. Administration of ammonium molybdate alone produced significant decline in the mean values of hemoglobin (Hb), packed cell volume (PCV), total leukocyte count (TLC), total erythrocyte count (TEC), and mean corpuscular hemoglobin concentration (MCHC), with a significant increase in neutrophil level and mean corpuscular volume (MCV). However, values of erythrocyte sedimentation rate, mean corpuscular hemoglobin, and differential leukocyte count were not significantly altered. On comparing observations of ameliorative group with the group 1 goats, it is concluded that the ameliorative copper salt has beneficial effects in alleviating the alterations in the values of Hb, PCV, TLC, TEC, MCV, MCHC, and neutrophils. SN - 0976-5131 UR - https://www.unboundmedicine.com/medline/citation/21170251/Haematolohical_profile_of_subacute_oral_toxicity_of_molybdenum_and_ameliorative_efficacy_of_copper_salt_in_goats_ L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21170251/ DB - PRIME DP - Unbound Medicine ER -
Try the Free App:
Prime PubMed app for iOS iPhone iPad
Prime PubMed app for Android
Prime PubMed is provided
free to individuals by:
Unbound Medicine.