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[Synchronous squamous cell carcinoma of the renal pelvis and squamous cell carcinoma of the ureter: report of two cases and review of literature].
Nan Fang Yi Ke Da Xue Xue Bao. 2010 Dec; 30(12):2765-7.NF

Abstract

OBJECTIVE

To study the clinicopathological characteristics of synchronous squamous cell carcinoma (SCC) of the renal pelvis and SCC of the ureter.

METHODS

The clinical data of two cases of synchronous SCC of the renal pelvis and SCC of the ureter were retrospectively reviewed and analyzed. In case 1, a 68-year-old man with hematuria for a month, imaging modalities revealed a right renal pelvis tumor and a right distal ureter tumor. The patient underwent nephroureterectomy and excision of the bladder cuff. Case 2, a 60-year-old man with the complaint of lower abdominal pain and left flank pain for a month, was diagnosed as left distal ureteral stone in another hospital. Ureterolithotomy was performed and a ureteral tumor was found at the lower site of the stone intraoperatively. The pathological report demonstrated SCC, and the patient was transferred to our hospital for further treatment. We found a left renal mass invading the left hemicolon during surgery, and nephroureterectomy was performed with a bladder cuff excision, left hemicolon resection, and also complete lymph node dissection. Neither of patients received adjuvant radiotherapy/chemotherapy.

RESULTS

Moderately differentiated SCC was reported in both of renal pelvis and ureter in case 1 and the tumor invaded the subepithelial connective tissue in the renal pelvis and superficial muscle in the ureter. In case 2, moderately differentiated SCC of the left renal pelvis with colon metastasis and poorly differentiated SCC of the ureter was reported with two retroperitoneal lymph node metastases. The two patients died from tumor recurrence and metastasis 5 and 6 months after the surgery, respectively.

CONCLUSION

Synchronous SCC of the renal pelvis and SCC of the ureter are rare and has high likeliness of early recurrence and metastasis, often with poor prognosis.

Authors+Show Affiliations

Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, China. chenzhuangfei@126.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
English Abstract
Journal Article
Review

Language

chi

PubMed ID

21177201

Citation

Chen, Zhuang-fei, et al. "[Synchronous Squamous Cell Carcinoma of the Renal Pelvis and Squamous Cell Carcinoma of the Ureter: Report of Two Cases and Review of Literature]." Nan Fang Yi Ke Da Xue Xue Bao = Journal of Southern Medical University, vol. 30, no. 12, 2010, pp. 2765-7.
Chen ZF, Zheng SB, Wu P, et al. [Synchronous squamous cell carcinoma of the renal pelvis and squamous cell carcinoma of the ureter: report of two cases and review of literature]. Nan Fang Yi Ke Da Xue Xue Bao. 2010;30(12):2765-7.
Chen, Z. F., Zheng, S. B., Wu, P., Zhang, P., Jiang, Y. D., Zhao, S. C., Mao, X. M., Chen, Z. R., & Shan, Z. F. (2010). [Synchronous squamous cell carcinoma of the renal pelvis and squamous cell carcinoma of the ureter: report of two cases and review of literature]. Nan Fang Yi Ke Da Xue Xue Bao = Journal of Southern Medical University, 30(12), 2765-7.
Chen ZF, et al. [Synchronous Squamous Cell Carcinoma of the Renal Pelvis and Squamous Cell Carcinoma of the Ureter: Report of Two Cases and Review of Literature]. Nan Fang Yi Ke Da Xue Xue Bao. 2010;30(12):2765-7. PubMed PMID: 21177201.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Synchronous squamous cell carcinoma of the renal pelvis and squamous cell carcinoma of the ureter: report of two cases and review of literature]. AU - Chen,Zhuang-fei, AU - Zheng,Shao-bin, AU - Wu,Peng, AU - Zhang,Peng, AU - Jiang,Yao-dong, AU - Zhao,Shan-chao, AU - Mao,Xiang-ming, AU - Chen,Ze-rong, AU - Shan,Zheng-fei, PY - 2010/12/24/entrez PY - 2010/12/24/pubmed PY - 2013/5/22/medline SP - 2765 EP - 7 JF - Nan fang yi ke da xue xue bao = Journal of Southern Medical University JO - Nan Fang Yi Ke Da Xue Xue Bao VL - 30 IS - 12 N2 - OBJECTIVE: To study the clinicopathological characteristics of synchronous squamous cell carcinoma (SCC) of the renal pelvis and SCC of the ureter. METHODS: The clinical data of two cases of synchronous SCC of the renal pelvis and SCC of the ureter were retrospectively reviewed and analyzed. In case 1, a 68-year-old man with hematuria for a month, imaging modalities revealed a right renal pelvis tumor and a right distal ureter tumor. The patient underwent nephroureterectomy and excision of the bladder cuff. Case 2, a 60-year-old man with the complaint of lower abdominal pain and left flank pain for a month, was diagnosed as left distal ureteral stone in another hospital. Ureterolithotomy was performed and a ureteral tumor was found at the lower site of the stone intraoperatively. The pathological report demonstrated SCC, and the patient was transferred to our hospital for further treatment. We found a left renal mass invading the left hemicolon during surgery, and nephroureterectomy was performed with a bladder cuff excision, left hemicolon resection, and also complete lymph node dissection. Neither of patients received adjuvant radiotherapy/chemotherapy. RESULTS: Moderately differentiated SCC was reported in both of renal pelvis and ureter in case 1 and the tumor invaded the subepithelial connective tissue in the renal pelvis and superficial muscle in the ureter. In case 2, moderately differentiated SCC of the left renal pelvis with colon metastasis and poorly differentiated SCC of the ureter was reported with two retroperitoneal lymph node metastases. The two patients died from tumor recurrence and metastasis 5 and 6 months after the surgery, respectively. CONCLUSION: Synchronous SCC of the renal pelvis and SCC of the ureter are rare and has high likeliness of early recurrence and metastasis, often with poor prognosis. SN - 1673-4254 UR - https://www.unboundmedicine.com/medline/citation/21177201/[Synchronous_squamous_cell_carcinoma_of_the_renal_pelvis_and_squamous_cell_carcinoma_of_the_ureter:_report_of_two_cases_and_review_of_literature]_ L2 - http://www.diseaseinfosearch.org/result/1077 DB - PRIME DP - Unbound Medicine ER -