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Frequency of light chain deposition nephropathy relative to renal amyloidosis and Bence Jones cast nephropathy in a necropsy study of patients with myeloma.
Arch Pathol Lab Med. 1990 Sep; 114(9):986-7.AP

Abstract

The frequency of light chain deposition nephropathy relative to renal amyloidosis and Bence Jones cast nephropathy was determined in a necropsy study of 57 patients with myeloma. The diagnosis of light chain deposition nephropathy was established by immunofluorescence microscopic examination of kidney tissue demonstrating linear deposits of a single light chain isotype along tubular and other renal basement membranes, and by electron microscopy, which showed the characteristic granular nature of the deposits. In this study, 3 patients (5%) had kappa light chain deposition nephropathy, 6 (11%) had renal amyloidosis, and 18 (32%) had Bence Jones cast nephropathy. The data indicate that light chain deposition nephropathy is a rare complication of multiple myeloma.

Authors+Show Affiliations

Department of Pathology, Albert Szent-Györgyi Medical University, Szeged, Hungary.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

2117910

Citation

Iványi, B. "Frequency of Light Chain Deposition Nephropathy Relative to Renal Amyloidosis and Bence Jones Cast Nephropathy in a Necropsy Study of Patients With Myeloma." Archives of Pathology & Laboratory Medicine, vol. 114, no. 9, 1990, pp. 986-7.
Iványi B. Frequency of light chain deposition nephropathy relative to renal amyloidosis and Bence Jones cast nephropathy in a necropsy study of patients with myeloma. Arch Pathol Lab Med. 1990;114(9):986-7.
Iványi, B. (1990). Frequency of light chain deposition nephropathy relative to renal amyloidosis and Bence Jones cast nephropathy in a necropsy study of patients with myeloma. Archives of Pathology & Laboratory Medicine, 114(9), 986-7.
Iványi B. Frequency of Light Chain Deposition Nephropathy Relative to Renal Amyloidosis and Bence Jones Cast Nephropathy in a Necropsy Study of Patients With Myeloma. Arch Pathol Lab Med. 1990;114(9):986-7. PubMed PMID: 2117910.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Frequency of light chain deposition nephropathy relative to renal amyloidosis and Bence Jones cast nephropathy in a necropsy study of patients with myeloma. A1 - Iványi,B, PY - 1990/9/1/pubmed PY - 1990/9/1/medline PY - 1990/9/1/entrez SP - 986 EP - 7 JF - Archives of pathology & laboratory medicine JO - Arch. Pathol. Lab. Med. VL - 114 IS - 9 N2 - The frequency of light chain deposition nephropathy relative to renal amyloidosis and Bence Jones cast nephropathy was determined in a necropsy study of 57 patients with myeloma. The diagnosis of light chain deposition nephropathy was established by immunofluorescence microscopic examination of kidney tissue demonstrating linear deposits of a single light chain isotype along tubular and other renal basement membranes, and by electron microscopy, which showed the characteristic granular nature of the deposits. In this study, 3 patients (5%) had kappa light chain deposition nephropathy, 6 (11%) had renal amyloidosis, and 18 (32%) had Bence Jones cast nephropathy. The data indicate that light chain deposition nephropathy is a rare complication of multiple myeloma. SN - 0003-9985 UR - https://www.unboundmedicine.com/medline/citation/2117910/Frequency_of_light_chain_deposition_nephropathy_relative_to_renal_amyloidosis_and_Bence_Jones_cast_nephropathy_in_a_necropsy_study_of_patients_with_myeloma_ L2 - http://www.diseaseinfosearch.org/result/380 DB - PRIME DP - Unbound Medicine ER -