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Evaluation of Antioxidant Potential of Melanthera scandens.
J Acupunct Meridian Stud. 2010 Dec; 3(4):267-71.JA

Abstract

A methanol extract of dried leaves of Melanthera scandens was examined for antioxidant activities using a variety of assays, including 1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging, reducing power, ferrous chelating, and ferric thiocyanate methods with ascorbic acid and EDTA as positive controls. The extract showed noticeable activities in most of these in vitro tests. The amount of phenolic compounds in the extract expressed in gallic acid equivalent was found to be 52.8 mg/g. The extract demonstrated inhibition of linoleic acid lipid peroxidation, active reducing power, and DPPH radical scavenging activities which were less than that of the positive controls. The extract also showed weaker iron chelating effect when compared with the EDTA positive control. The present results showed that M. scandens leaf extract possessed antioxidant properties and this plant is a potential useful source of natural antioxidants.

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Authors+Show Affiliations

Adesegun SA
Department of Pharmacognosy, Faculty of Pharmacy, University of Lagos, Lagos, Nigeria. asegun67@yahoo.com
Alabi SO
No affiliation info available
Olabanji PT
No affiliation info available
Coker HA
No affiliation info available

MeSH

AsteraceaeFree Radical ScavengersPlant ExtractsPlant Leaves

Pub Type(s)

Journal Article

Language

eng

PubMed ID

21185542

Citation

Adesegun, Sunday Adeleke, et al. "Evaluation of Antioxidant Potential of Melanthera Scandens." Journal of Acupuncture and Meridian Studies, vol. 3, no. 4, 2010, pp. 267-71.
Adesegun SA, Alabi SO, Olabanji PT, et al. Evaluation of Antioxidant Potential of Melanthera scandens. J Acupunct Meridian Stud. 2010;3(4):267-71.
Adesegun, S. A., Alabi, S. O., Olabanji, P. T., & Coker, H. A. (2010). Evaluation of Antioxidant Potential of Melanthera scandens. Journal of Acupuncture and Meridian Studies, 3(4), 267-71. https://doi.org/10.1016/S2005-2901(10)60047-7
Adesegun SA, et al. Evaluation of Antioxidant Potential of Melanthera Scandens. J Acupunct Meridian Stud. 2010;3(4):267-71. PubMed PMID: 21185542.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Evaluation of Antioxidant Potential of Melanthera scandens. AU - Adesegun,Sunday Adeleke, AU - Alabi,Sukurat Olasumbo, AU - Olabanji,Patricia Taiwo, AU - Coker,Herbert Alexander Babatunde, PY - 2010/06/22/received PY - 2010/10/12/accepted PY - 2010/12/28/entrez PY - 2010/12/28/pubmed PY - 2011/4/5/medline SP - 267 EP - 71 JF - Journal of acupuncture and meridian studies JO - J Acupunct Meridian Stud VL - 3 IS - 4 N2 - A methanol extract of dried leaves of Melanthera scandens was examined for antioxidant activities using a variety of assays, including 1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging, reducing power, ferrous chelating, and ferric thiocyanate methods with ascorbic acid and EDTA as positive controls. The extract showed noticeable activities in most of these in vitro tests. The amount of phenolic compounds in the extract expressed in gallic acid equivalent was found to be 52.8 mg/g. The extract demonstrated inhibition of linoleic acid lipid peroxidation, active reducing power, and DPPH radical scavenging activities which were less than that of the positive controls. The extract also showed weaker iron chelating effect when compared with the EDTA positive control. The present results showed that M. scandens leaf extract possessed antioxidant properties and this plant is a potential useful source of natural antioxidants. SN - 2093-8152 UR - https://www.unboundmedicine.com/medline/citation/21185542/Evaluation_of_Antioxidant_Potential_of_Melanthera_scandens_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S2005-2901(10)60047-7 DB - PRIME DP - Unbound Medicine ER -