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The specific IgE reactivity pattern of weed pollen-induced allergic rhinitis patients.
Acta Otolaryngol. 2011 May; 131(5):533-8.AO

Abstract

CONCLUSION

Specific immunoglobulin E (IgE) reactivity towards the major mugwort allergen Art v 1 is a good indicator for Art v sensitization. Allergens from the ragweed species Amb t and Amb a possibly share common IgE-binding epitopes.

OBJECTIVE

The aim of this study was to investigate the reactivity pattern of IgE in Chinese patients with weed pollen-induced allergic rhinitis.

METHODS

Sera from 50 weed pollen-induced allergic rhinitis patients were tested for specific serum IgE reactivity against allergenic extracts of mugwort (Artemisia vulgaris, Art v), short ragweed (Ambrosia artemisiifolia, Amb a), giant ragweed (Ambrosia trifida, Amb t), and single allergens of Art v 1, Art v 3, Amb a 1, and profilin.

RESULTS

Sera from 88% of the patients demonstrated positive specific IgE reactivity to Art v, and of these 82% were positive to Art v 1. Sera from 38% of the patients showed positive specific IgE reactivity to both ragweed species Amb t and Amb a. A strong correlation was found between the specific IgE levels of Amb t and Amb a. Of the Amb a IgE-positive patients, 38% were positive for Amb a 1. Of all patient sera tested, 12% were specific IgE-positive to profilin.

Authors+Show Affiliations

Department of Otolaryngology, Head and Neck Surgery, Beijing TongRen Hospital, Beijing Institute of Otolaryngology, Capital Medical University, No. 17 HouGouHuTong, Beijing, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21189055

Citation

Han, Demin, et al. "The Specific IgE Reactivity Pattern of Weed Pollen-induced Allergic Rhinitis Patients." Acta Oto-laryngologica, vol. 131, no. 5, 2011, pp. 533-8.
Han D, Lai X, Gjesing B, et al. The specific IgE reactivity pattern of weed pollen-induced allergic rhinitis patients. Acta Otolaryngol. 2011;131(5):533-8.
Han, D., Lai, X., Gjesing, B., Zhong, N., Zhang, L., & Spangfort, M. D. (2011). The specific IgE reactivity pattern of weed pollen-induced allergic rhinitis patients. Acta Oto-laryngologica, 131(5), 533-8. https://doi.org/10.3109/00016489.2010.539265
Han D, et al. The Specific IgE Reactivity Pattern of Weed Pollen-induced Allergic Rhinitis Patients. Acta Otolaryngol. 2011;131(5):533-8. PubMed PMID: 21189055.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The specific IgE reactivity pattern of weed pollen-induced allergic rhinitis patients. AU - Han,Demin, AU - Lai,Xuxin, AU - Gjesing,Birgitte, AU - Zhong,Nanshan, AU - Zhang,Luo, AU - Spangfort,Michael D, Y1 - 2010/12/28/ PY - 2010/12/30/entrez PY - 2010/12/30/pubmed PY - 2011/8/13/medline SP - 533 EP - 8 JF - Acta oto-laryngologica JO - Acta Otolaryngol. VL - 131 IS - 5 N2 - CONCLUSION: Specific immunoglobulin E (IgE) reactivity towards the major mugwort allergen Art v 1 is a good indicator for Art v sensitization. Allergens from the ragweed species Amb t and Amb a possibly share common IgE-binding epitopes. OBJECTIVE: The aim of this study was to investigate the reactivity pattern of IgE in Chinese patients with weed pollen-induced allergic rhinitis. METHODS: Sera from 50 weed pollen-induced allergic rhinitis patients were tested for specific serum IgE reactivity against allergenic extracts of mugwort (Artemisia vulgaris, Art v), short ragweed (Ambrosia artemisiifolia, Amb a), giant ragweed (Ambrosia trifida, Amb t), and single allergens of Art v 1, Art v 3, Amb a 1, and profilin. RESULTS: Sera from 88% of the patients demonstrated positive specific IgE reactivity to Art v, and of these 82% were positive to Art v 1. Sera from 38% of the patients showed positive specific IgE reactivity to both ragweed species Amb t and Amb a. A strong correlation was found between the specific IgE levels of Amb t and Amb a. Of the Amb a IgE-positive patients, 38% were positive for Amb a 1. Of all patient sera tested, 12% were specific IgE-positive to profilin. SN - 1651-2251 UR - https://www.unboundmedicine.com/medline/citation/21189055/The_specific_IgE_reactivity_pattern_of_weed_pollen_induced_allergic_rhinitis_patients_ L2 - http://www.tandfonline.com/doi/full/10.3109/00016489.2010.539265 DB - PRIME DP - Unbound Medicine ER -