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Clinical significance of human papilloma virus infection in the cervical lesions.
Front Med China. 2010 Sep; 4(3):264-70.FM

Abstract

Cervical lesions have been regarded as the common and frequently occurring diseases in China. Recently, the morbidity and youth tendency of cervical cancer have gradually increased. Cervical cancer, related with human papilloma virus (HPV) infection, has been one of the severest diseases threatening health and life of women, and is an infectious disease. The universality of HPV infection in the reproductive tract should not be ignored. The well-known risk factors of HPV infection in cervical lesions consist of high-risk sexual behaviors, immunosuppression, age, contraceptive methods, the concurrent infection of other sexually transmitted diseases, etc. The variation of cervical lesions induced by HPV infection is involved in the continuous pathological process, including the subclinical, latent, and persistent infection of high risk (HR)-HPV, chronic cervicitis with abnormal results of cytological examination, cervical intraepithelial neoplasia (CIN), and cervical cancer. The outcome of patients with HPV infection is influenced by many factors, such as HPV subtype dominance, persistent HPV infection, HPV loading dose, and multiple HPV infection. Controlling HR-HPV persistent infection should be an important strategy for reducing cervical lesions.

Authors+Show Affiliations

Cancer Biology Research Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

21191829

Citation

Li, Shuang, et al. "Clinical Significance of Human Papilloma Virus Infection in the Cervical Lesions." Frontiers of Medicine in China, vol. 4, no. 3, 2010, pp. 264-70.
Li S, Meng YH, Ting H, et al. Clinical significance of human papilloma virus infection in the cervical lesions. Front Med China. 2010;4(3):264-70.
Li, S., Meng, Y. H., Ting, H., Shen, J., & Ma, D. (2010). Clinical significance of human papilloma virus infection in the cervical lesions. Frontiers of Medicine in China, 4(3), 264-70. https://doi.org/10.1007/s11684-010-0094-6
Li S, et al. Clinical Significance of Human Papilloma Virus Infection in the Cervical Lesions. Front Med China. 2010;4(3):264-70. PubMed PMID: 21191829.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinical significance of human papilloma virus infection in the cervical lesions. AU - Li,Shuang, AU - Meng,Yu-Han, AU - Ting,Hu, AU - Shen,Jian, AU - Ma,Ding, Y1 - 2010/07/16/ PY - 2010/05/11/received PY - 2010/05/20/accepted PY - 2010/12/31/entrez PY - 2010/12/31/pubmed PY - 2011/5/14/medline SP - 264 EP - 70 JF - Frontiers of medicine in China JO - Front Med China VL - 4 IS - 3 N2 - Cervical lesions have been regarded as the common and frequently occurring diseases in China. Recently, the morbidity and youth tendency of cervical cancer have gradually increased. Cervical cancer, related with human papilloma virus (HPV) infection, has been one of the severest diseases threatening health and life of women, and is an infectious disease. The universality of HPV infection in the reproductive tract should not be ignored. The well-known risk factors of HPV infection in cervical lesions consist of high-risk sexual behaviors, immunosuppression, age, contraceptive methods, the concurrent infection of other sexually transmitted diseases, etc. The variation of cervical lesions induced by HPV infection is involved in the continuous pathological process, including the subclinical, latent, and persistent infection of high risk (HR)-HPV, chronic cervicitis with abnormal results of cytological examination, cervical intraepithelial neoplasia (CIN), and cervical cancer. The outcome of patients with HPV infection is influenced by many factors, such as HPV subtype dominance, persistent HPV infection, HPV loading dose, and multiple HPV infection. Controlling HR-HPV persistent infection should be an important strategy for reducing cervical lesions. SN - 1673-7458 UR - https://www.unboundmedicine.com/medline/citation/21191829/Clinical_significance_of_human_papilloma_virus_infection_in_the_cervical_lesions. L2 - https://medlineplus.gov/cervixdisorders.html DB - PRIME DP - Unbound Medicine ER -