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Electrochemical detection of honokiol and magnolol in traditional Chinese medicines using acetylene black nanoparticle-modified electrode.
Phytochem Anal. 2011 Jul-Aug; 22(4):291-5.PA

Abstract

INTRODUCTION

Honokiol and magnolol are the active components of Magnolia officinalis, which is a widely used traditional Chinese medicine. Their simultaneous analysis is, therefore, important for the quality control of the product.

OBJECTIVE

To establish a simple, sensitive and rapid electrochemical method for the simultaneous detection of honokiol and magnolol based on the remarkable enhancement effect of acetylene black nanoparticle (AB).

METHODOLOGY

The AB-modified electrode was prepared via solvent evaporation. The electrochemical response of honokiol and magnolol was investigated using cyclic voltammetry. The simultaneous detection was performed with differential pulse voltammetry. The method was validated in terms of linearity, sensitivity, precision and accuracy.

RESULTS

The linear range for honokiol is 0.5-300 µg/L, and the limit of detection (LOD) is 0.25 µg/L (9.4 × 10(-10) mol/L). For magnolol, the linear range is 10-250 µg/L, and the LOD is 5 µg/L (1.88 × 10(-8) mol/L).

CONCLUSION

The new method was successfully used to determine honokiol and magnolol in a traditional Chinese medicine called Ageratum liquid.

Links

Publisher Full Text (DOI)

Authors+Show Affiliations

Yang X
School of Pharmacy, Wenzhou Medical College, Wenzhou 325000, People's Republic of China. yang_xiaofeng@163.com
Gao M
No affiliation info available
Hu H
No affiliation info available
Zhang H
No affiliation info available

MeSH

AcetyleneBiphenyl CompoundsDrugs, Chinese HerbalElectrochemistryElectrodesLignansMagnoliaMedicine, Chinese TraditionalMicroscopy, Electron, ScanningNanoparticlesOxidation-Reduction

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21204152

Citation

Yang, Xiaofeng, et al. "Electrochemical Detection of Honokiol and Magnolol in Traditional Chinese Medicines Using Acetylene Black Nanoparticle-modified Electrode." Phytochemical Analysis : PCA, vol. 22, no. 4, 2011, pp. 291-5.
Yang X, Gao M, Hu H, et al. Electrochemical detection of honokiol and magnolol in traditional Chinese medicines using acetylene black nanoparticle-modified electrode. Phytochem Anal. 2011;22(4):291-5.
Yang, X., Gao, M., Hu, H., & Zhang, H. (2011). Electrochemical detection of honokiol and magnolol in traditional Chinese medicines using acetylene black nanoparticle-modified electrode. Phytochemical Analysis : PCA, 22(4), 291-5. https://doi.org/10.1002/pca.1279
Yang X, et al. Electrochemical Detection of Honokiol and Magnolol in Traditional Chinese Medicines Using Acetylene Black Nanoparticle-modified Electrode. Phytochem Anal. 2011 Jul-Aug;22(4):291-5. PubMed PMID: 21204152.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Electrochemical detection of honokiol and magnolol in traditional Chinese medicines using acetylene black nanoparticle-modified electrode. AU - Yang,Xiaofeng, AU - Gao,Miaomiao, AU - Hu,Haidong, AU - Zhang,Huajie, Y1 - 2010/12/30/ PY - 2010/07/14/received PY - 2010/09/05/revised PY - 2010/09/11/accepted PY - 2011/1/5/entrez PY - 2011/1/5/pubmed PY - 2011/10/4/medline SP - 291 EP - 5 JF - Phytochemical analysis : PCA JO - Phytochem Anal VL - 22 IS - 4 N2 - INTRODUCTION: Honokiol and magnolol are the active components of Magnolia officinalis, which is a widely used traditional Chinese medicine. Their simultaneous analysis is, therefore, important for the quality control of the product. OBJECTIVE: To establish a simple, sensitive and rapid electrochemical method for the simultaneous detection of honokiol and magnolol based on the remarkable enhancement effect of acetylene black nanoparticle (AB). METHODOLOGY: The AB-modified electrode was prepared via solvent evaporation. The electrochemical response of honokiol and magnolol was investigated using cyclic voltammetry. The simultaneous detection was performed with differential pulse voltammetry. The method was validated in terms of linearity, sensitivity, precision and accuracy. RESULTS: The linear range for honokiol is 0.5-300 µg/L, and the limit of detection (LOD) is 0.25 µg/L (9.4 × 10(-10) mol/L). For magnolol, the linear range is 10-250 µg/L, and the LOD is 5 µg/L (1.88 × 10(-8) mol/L). CONCLUSION: The new method was successfully used to determine honokiol and magnolol in a traditional Chinese medicine called Ageratum liquid. SN - 1099-1565 UR - https://www.unboundmedicine.com/medline/citation/21204152/Electrochemical_detection_of_honokiol_and_magnolol_in_traditional_Chinese_medicines_using_acetylene_black_nanoparticle_modified_electrode_ L2 - https://doi.org/10.1002/pca.1279 DB - PRIME DP - Unbound Medicine ER -