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Derivation of anthropometric cut-off levels to define CVD risk in Sri Lankan adults.
Br J Nutr 2011; 105(7):1084-90BJ

Abstract

Obesity is associated with increased cardiovascular risk. Anthropometric cut-off values derived for Caucasians may not be applicable to other populations. The main objective of the present study was to derive population-specific anthropometric cut-off values to define high CVD risk for Sri Lankan adults. A nationally representative sample of 4474 non-institutionalised adults aged ≥ 18 years was analysed. Cut-off values to provide optimum sensitivity and specificity were derived using receiver-operating characteristic curve analysis. BMI, waist circumference (WC), waist-to-hip ratio (WHR), blood pressure and overnight fasting venous blood samples were collected to measure glucose, HDL-cholesterol and TAG. An oral glucose tolerance test was also performed. The results suggested that the age-adjusted BMI, WC and WHR were significantly associated with all cardiovascular risk factors (P < 0·001). Cut-off values for BMI, WC and WHR for males were 20·7 kg/m2, 76·5 cm and 0·89, respectively. The respective values for females were 22·0 kg/m2, 76·3 cm and 0·85. The common cut-off value for BMI for males and females was 21·5 kg/m2. Similarly, WC and WHR cut-off values for both males and females were 76·3 cm and 0·87, respectively. The Asian and Caucasian anthropometric cut-off levels showed lower sensitivity and higher false negative percentage compared with newly derived cut-off levels. In conclusion, BMI, WC and WHR were all associated with increased CVD risk. We propose the following anthropometric cut-off points to determine high CVD risk level for Sri Lankan adults: BMI ≥ 21·5 kg/m2, WC ≥ 76 cm and WHR ≥ 0·85 (women) and 0·90 (men).

Authors+Show Affiliations

Diabetes Research Unit, Department of Clinical Medicine, Faculty of Medicine, University of Colombo, Kynsey Road, Colombo 8, Sri Lanka. pkatulanda@yahoo.comNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21205381

Citation

Katulanda, P, et al. "Derivation of Anthropometric Cut-off Levels to Define CVD Risk in Sri Lankan Adults." The British Journal of Nutrition, vol. 105, no. 7, 2011, pp. 1084-90.
Katulanda P, Jayawardena MA, Sheriff MH, et al. Derivation of anthropometric cut-off levels to define CVD risk in Sri Lankan adults. Br J Nutr. 2011;105(7):1084-90.
Katulanda, P., Jayawardena, M. A., Sheriff, M. H., & Matthews, D. R. (2011). Derivation of anthropometric cut-off levels to define CVD risk in Sri Lankan adults. The British Journal of Nutrition, 105(7), pp. 1084-90. doi:10.1017/S0007114510004563.
Katulanda P, et al. Derivation of Anthropometric Cut-off Levels to Define CVD Risk in Sri Lankan Adults. Br J Nutr. 2011;105(7):1084-90. PubMed PMID: 21205381.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Derivation of anthropometric cut-off levels to define CVD risk in Sri Lankan adults. AU - Katulanda,P, AU - Jayawardena,M A R, AU - Sheriff,M H R, AU - Matthews,D R, Y1 - 2010/12/17/ PY - 2011/1/6/entrez PY - 2011/1/6/pubmed PY - 2011/5/6/medline SP - 1084 EP - 90 JF - The British journal of nutrition JO - Br. J. Nutr. VL - 105 IS - 7 N2 - Obesity is associated with increased cardiovascular risk. Anthropometric cut-off values derived for Caucasians may not be applicable to other populations. The main objective of the present study was to derive population-specific anthropometric cut-off values to define high CVD risk for Sri Lankan adults. A nationally representative sample of 4474 non-institutionalised adults aged ≥ 18 years was analysed. Cut-off values to provide optimum sensitivity and specificity were derived using receiver-operating characteristic curve analysis. BMI, waist circumference (WC), waist-to-hip ratio (WHR), blood pressure and overnight fasting venous blood samples were collected to measure glucose, HDL-cholesterol and TAG. An oral glucose tolerance test was also performed. The results suggested that the age-adjusted BMI, WC and WHR were significantly associated with all cardiovascular risk factors (P < 0·001). Cut-off values for BMI, WC and WHR for males were 20·7 kg/m2, 76·5 cm and 0·89, respectively. The respective values for females were 22·0 kg/m2, 76·3 cm and 0·85. The common cut-off value for BMI for males and females was 21·5 kg/m2. Similarly, WC and WHR cut-off values for both males and females were 76·3 cm and 0·87, respectively. The Asian and Caucasian anthropometric cut-off levels showed lower sensitivity and higher false negative percentage compared with newly derived cut-off levels. In conclusion, BMI, WC and WHR were all associated with increased CVD risk. We propose the following anthropometric cut-off points to determine high CVD risk level for Sri Lankan adults: BMI ≥ 21·5 kg/m2, WC ≥ 76 cm and WHR ≥ 0·85 (women) and 0·90 (men). SN - 1475-2662 UR - https://www.unboundmedicine.com/medline/citation/21205381/Derivation_of_anthropometric_cut_off_levels_to_define_CVD_risk_in_Sri_Lankan_adults_ L2 - https://www.cambridge.org/core/product/identifier/S0007114510004563/type/journal_article DB - PRIME DP - Unbound Medicine ER -